Automatic time-lapse instrument is superior to single-point morphology observation for selecting viable embryos: retrospective study in oocyte donation

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Presentation transcript:

Automatic time-lapse instrument is superior to single-point morphology observation for selecting viable embryos: retrospective study in oocyte donation Belén Aparicio-Ruiz, Ph.D., Natalia Basile, Ph.D., Sonia Pérez Albalá, Ph.D., Fernando Bronet, Ph.D., José Remohí, M.D., Marcos Meseguer, Ph.D. Fertility and Sterility Volume 106, Issue 6, Pages 1379-1385.e10 (November 2016) DOI: 10.1016/j.fertnstert.2016.07.1117 Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 1 (A) Early Embryo Viability Assessment (EEVA) classification of known implantation (KID) embryos. (B) Implantation rates of KID embryos according to day of transfer in the different EEVA categories, in both cases with P<.05. Fertility and Sterility 2016 106, 1379-1385.e10DOI: (10.1016/j.fertnstert.2016.07.1117) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 2 (1) Ongoing pregnancy rate when at least one transferred embryo was high according to Early Embryo Viability Assessment (EEVA) or none were high. (2) The ongoing pregnancy when at least one transferred embryo was rated A according to Asociación para el Estudio de la Biología de la Reproducción (ASEBIR) or none were rated A. *P<.001. Fertility and Sterility 2016 106, 1379-1385.e10DOI: (10.1016/j.fertnstert.2016.07.1117) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 1 Early Embryo Viability Assessment (EEVA) classification of embryos on day 3 according to P2 and P3 values. P2 = time from division to 2 cells to division to 3 cells; P3 = time from division to 3 cells to division to 4 cells. Fertility and Sterility 2016 106, 1379-1385.e10DOI: (10.1016/j.fertnstert.2016.07.1117) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 2 Asociación para el Estudio de la Biología de la Reproducción (ASEBIR) classification of blastocysts on day 5 according to expansion, inner cell mass, and trophectoderm quality. Fertility and Sterility 2016 106, 1379-1385.e10DOI: (10.1016/j.fertnstert.2016.07.1117) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 3 ASEBIR morphology classification of known implantation (KID) embryos on day of transfer. ASEBIR = Asociación para el Estudio de la Biología de la Reproducción. Fertility and Sterility 2016 106, 1379-1385.e10DOI: (10.1016/j.fertnstert.2016.07.1117) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 4 Implantation rates of day 3 and day 5 transfers according to ASEBIR day 3 (P<.05) and day 5 (P<.05) morphology categories. ASEBIR = Asociación para el Estudio de la Biología de la Reproducción. Fertility and Sterility 2016 106, 1379-1385.e10DOI: (10.1016/j.fertnstert.2016.07.1117) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions