Tfr cells’ transcriptomic profile distinguishes them from Treg and Tfh cells. Tfr cells’ transcriptomic profile distinguishes them from Treg and Tfh cells.

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Tfr cells’ transcriptomic profile distinguishes them from Treg and Tfh cells. Tfr cells’ transcriptomic profile distinguishes them from Treg and Tfh cells. (A) Heat map comparing the gene expression profiles of Treg (green), Tfr (blue), and Tfh (black) cells from two genetic backgrounds after immunization. Red, high gene expression; blue, low gene expression. (B) Dendrogram of Treg, Tfr, and Tfh cells representing the hierarchical cluster analysis performed with the pvclust R package. Paul-Gydeon G. Ritvo et al. Sci. Immunol. 2017;2:eaan0368 Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works