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Volume 19, Issue 1, Pages 35-42 (February 2012) Antihyperglycemic, antihyperlipidemic and antioxidant activities of traditional aqueous extract of Zygophyllum album in streptozotocin diabetic mice Jamel El Ghoul, Moêz Smiri, Saad Ghrab, Naceur A. Boughattas, Mossadok Ben-Attia Pathophysiology Volume 19, Issue 1, Pages 35-42 (February 2012) DOI: 10.1016/j.pathophys.2011.12.001 Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Effect of aqueous extract of Zygophyllum album on blood glucose level in STZ-induced diabetic mice. The data are expressed as means±S.D. (n=8). Values are statistically significant at p<0.05. aDiabetic control vs. control. bDiabetic+Zygophyllum album extract 100mg/kg vs. cdiabetic control. Diabetic+Zygophyllum album extract 300mg/kg vs. diabetic control. dDiabetic+gliclazide vs. diabetic control. Pathophysiology 2012 19, 35-42DOI: (10.1016/j.pathophys.2011.12.001) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Effect of aqueous extract of Zygophyllum album on lipid peroxidation (MDA) in liver (A) and pancreas (B) in STZ-induced diabetic mice. The data are expressed as means±S.D. (n=8). Values are statistically significant at p<0.05. aDiabetic control vs. control. bDiabetic+Zygophyllum album extract 100mg/kg vs. cdiabetic control. Diabetic+Zygophyllum album extract 300mg/kg vs. diabetic control. dDiabetic+gliclazide vs. diabetic control. Pathophysiology 2012 19, 35-42DOI: (10.1016/j.pathophys.2011.12.001) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions

Fig. 3 Effect of aqueous extract of Zygophyllum album on serum vitamin C (A) and vitamin E (B) level in STZ-induced diabetic mice. The data are expressed as means±S.D. (n=8). Values are statistically significant at p<0.05. aDiabetic control vs. control. bDiabetic+Zygophyllum album extract 100mg/kg vs. diabetic control. cDiabetic+Zygophyllum album extract 300mg/kg vs. diabetic control. dDiabetic+gliclazide vs. diabetic control. Pathophysiology 2012 19, 35-42DOI: (10.1016/j.pathophys.2011.12.001) Copyright © 2011 Elsevier Ireland Ltd Terms and Conditions