Degree of synovitis on MRI by comprehensive whole knee semi-quantitative scoring method correlates with histologic and macroscopic features of synovial.

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Degree of synovitis on MRI by comprehensive whole knee semi-quantitative scoring method correlates with histologic and macroscopic features of synovial tissue inflammation in knee osteoarthritis B.J.E. de Lange-Brokaar, A. Ioan-Facsinay, E. Yusuf, A.W. Visser, H.M. Kroon, S.N. Andersen, L. Herb-van Toorn, G.J.V.M. van Osch, A.-M. Zuurmond, V. Stojanovic-Susulic, J.L. Bloem, R.G.H.H. Nelissen, T.W.J. Huizinga, M. Kloppenburg Osteoarthritis and Cartilage Volume 22, Issue 10, Pages 1606-1613 (October 2014) DOI: 10.1016/j.joca.2013.12.013 Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Scoring system for scoring histology features based on own samples. Representative pictures of synovial tissue samples with H&E staining of all three features: lining layer, stroma and infiltrate. Grade 0 (normal) and Grade 3 (most severe) sample for each feature are shown. Osteoarthritis and Cartilage 2014 22, 1606-1613DOI: (10.1016/j.joca.2013.12.013) Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Examples of histology features (H&E staining) and CE-MRI from a patient from the arthroscopy group and a patient from the arthroplasty group. Patient from the arthroscopy group displaying a mild synovitis and patient from the arthroplasty displaying a severe synovitis. Both histology features and CE-MR images are shown. Open black arrow = hyperplasia lining layer, Black arrow = infiltrate, open white arrow = Bakers Cyst with synovial thickening, white arrow = synovial inflammation. Osteoarthritis and Cartilage 2014 22, 1606-1613DOI: (10.1016/j.joca.2013.12.013) Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions