Rapid acquisition of decreased carbapenem susceptibility in a strain of Klebsiella pneumoniae arising during meropenem therapy J. Findlay, A. Hamouda,

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Rapid acquisition of decreased carbapenem susceptibility in a strain of Klebsiella pneumoniae arising during meropenem therapy J. Findlay, A. Hamouda, S.J. Dancer, S.G.B. Amyes Clinical Microbiology and Infection Volume 18, Issue 2, Pages 140-146 (February 2012) DOI: 10.1111/j.1469-0691.2011.03515.x Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 The pulsed-field typing of K1 and K2 after digestion with XbaI. Clinical Microbiology and Infection 2012 18, 140-146DOI: (10.1111/j.1469-0691.2011.03515.x) Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 A section of an SDS PAGE gel showing the major OMPs in K1, K2, ATCC 13883, MGH78578, an MGH78578 meropenem mutant and a K1 meropenem mutant. NB, nutrient broth; LB, Luria-Bertani broth. Clinical Microbiology and Infection 2012 18, 140-146DOI: (10.1111/j.1469-0691.2011.03515.x) Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 3 The expression of the selected genes in K1, K2 and ATCC 13883. NB, nutrient broth; LB, Luria-Bertani broth. Clinical Microbiology and Infection 2012 18, 140-146DOI: (10.1111/j.1469-0691.2011.03515.x) Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions