Unlocking Collagen Proteolysis with a Gentle Pull

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Presentation transcript:

Unlocking Collagen Proteolysis with a Gentle Pull Laurent Kreplak, Andrew D. Rutenberg  Biophysical Journal  Volume 114, Issue 3, Pages 503-504 (February 2018) DOI: 10.1016/j.bpj.2017.11.3788 Copyright © 2017 Biophysical Society Terms and Conditions

Figure 1 Centrifuge force microscopy coupled with careful surface chemistry to achieve single-molecule collagen-tethering (A) opens the road for proteolytic assays under constant force. In the case of collagen-III (B), this assay demonstrates force-induced proteolytic activity of trypsin (2). To see this figure in color, go online. Biophysical Journal 2018 114, 503-504DOI: (10.1016/j.bpj.2017.11.3788) Copyright © 2017 Biophysical Society Terms and Conditions

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