Association of the very early rise of human chorionic gonadotropin with adverse outcomes in singleton pregnancies after in vitro fertilization Christopher.

Slides:

Advertisements

Similar presentations

Clarisa R. Gracia, M. D. , M. S. C. E. , Christopher B. Morse, B. A

Advertisements

Lisa Marii Cookingham, M. D. , Rachel P. Goossen, B. A. , Amy E. T

The effectiveness of gonadotropin-releasing hormone antagonist in poor ovarian responders undergoing in vitro fertilization: a systematic review and meta-analysis

Grace Younes, M.D., Togas Tulandi, M.D., M.H.C.M.

Krinos M. Trokoudes, M. D. , Constantinos Pavlides, M. Sc

Demián Glujovsky, M.D., M.Sc., Cynthia Farquhar, M.D., M.P.H.

What is a difficult transfer

A giant oocyte in a cohort of retrieved oocytes: does it have any effect on the in vitro fertilization cycle outcome? Ronit Machtinger, M.D., Joseph.

Obstetric and perinatal outcomes in singleton pregnancies resulting from the transfer of blastocyst-stage versus cleavage-stage embryos generated through.

Cost-effectiveness of presumptively medically treating women at risk for ectopic pregnancy compared with first performing a dilatation and curettage

Clarisa R. Gracia, M. D. , M. S. C. E. , Christopher B. Morse, B. A

Recurrent IVF failure: other factors

Obstetric and perinatal outcomes after either fresh or thawed frozen embryo transfer: an analysis of 112,432 singleton pregnancies recorded in the Human.

Patient and cycle characteristics predicting high pregnancy rates with single-embryo transfer: an analysis of the Society for Assisted Reproductive Technology.

Samuel Santos-Ribeiro, M. D. , Johannie Siffain, M. D. , Nikolaos P

Endometrin as luteal phase support in assisted reproduction

Performance of human chorionic gonadotropin curves in women at risk for ectopic pregnancy: exceptions to the rules Christopher B. Morse, B.A., Mary D.

Intrauterine injection of human chorionic gonadotropin before embryo transfer significantly improves the implantation and pregnancy rates in in vitro.

Adherence compounds in embryo transfer media for assisted reproductive technologies: summary of a Cochrane review Stephan Bontekoe, M.D., Neil Johnson,

Contrasting patterns in in vitro fertilization pregnancy rates among fresh autologous, fresh oocyte donor, and cryopreserved cycles with the use of day.

Is frozen embryo transfer cycle associated with a significantly lower incidence of ectopic pregnancy? An analysis of more than 30,000 cycles Bo Huang,

Antimüllerian hormone as a predictor of live birth following assisted reproduction: an analysis of 85,062 fresh and thawed cycles from the Society for.

Cutoff value of human chorionic gonadotropin in relation to the number of methotrexate cycles in the successful treatment of ectopic pregnancy Ewa Nowak-Markwitz,

The relative contribution of assisted reproductive technologies and ovulation induction to multiple births in the United States 5 years after the Society.

Live birth of twins derived from zona-free oocytes

Grant D.E. McWilliams, D.O., John L. Frattarelli, M.D.

Insurance mandates and trends in infertility treatments

Application of redefined human chorionic gonadotropin curves for the diagnosis of women at risk for ectopic pregnancy Beata E. Seeber, M.D., Mary D.

Randomized, controlled pilot trial of natural versus hormone replacement therapy cycles in frozen embryo replacement in vitro fertilization Ginny Mounce,

Pregnancy-related complications and perinatal outcomes resulting from transfer of cryopreserved versus fresh embryos in vitro fertilization: a meta-analysis

Subtle progesterone rise on the day of human chorionic gonadotropin administration is associated with lower live birth rates in women undergoing assisted.

How and when human chorionic gonadotropin curves in women with an ectopic pregnancy mimic other outcomes: differences by race and ethnicity Katherine.

Alka Prakash, M. D. , Susan Laird, Ph. D. , Elizabeth Tuckerman, M. Sc

Establishing a human chorionic gonadotropin cutoff to guide methotrexate treatment of ectopic pregnancy: a systematic review Seema Menon, M.D., John.

Lisa Marii Cookingham, M. D. , Rachel P. Goossen, B. A. , Amy E. T

The effectiveness of gonadotropin-releasing hormone antagonist in poor ovarian responders undergoing in vitro fertilization: a systematic review and meta-analysis

Obstetric and perinatal outcomes in singleton pregnancies resulting from the transfer of frozen thawed versus fresh embryos generated through in vitro.

Epidemiology of male and female reproductive disorders and impact on fertility regulation and population growth Kurt T. Barnhart, M.D., M.S.C.E. Fertility.

Nigel Pereira, M. D. , Hency H. Patel, B. S. , Logan D. Stone, B. A

Programming the endometrium for deferred transfer of cryopreserved embryos: hormone replacement versus modified natural cycles Eva R. Groenewoud, M.D.,

What are patients doing with their mosaic embryos

Using the Society for Assisted Reproductive Technology Clinic Outcome System morphological measures to predict live birth after assisted reproductive.

Beata Seeber, M. D. , M. S. C. E. , Mary D. Sammel, Sc. D

Should embryos developing to blastocysts on day 7 be cryopreserved and transferred: an analysis of pregnancy and implantation rates George Kovalevsky,

Use of “2-dose” regimen of methotrexate to treat ectopic pregnancy

Gonadotropin-releasing hormone antagonist use is associated with increased pregnancy rates in ovulation induction–intrauterine insemination to in vitro.

Efficacy and safety of human chorionic gonadotropin for follicular phase stimulation in assisted reproduction: a systematic review and meta-analysis

Jennifer F. Kawwass, M. D. , Sara Crawford, Ph. D. , Donna R

Birth weight is associated with inner cell mass grade of blastocysts

Aaron K. Styer, M. D. , Diane L. Wright, Ph. D. , H. C. L. D. , Anne M

Live babies born per oocyte retrieved in a subpopulation of oocyte donors with repetitive reproductive success J. Ryan Martin, M.D., Jason G. Bromer,

David E. Reichman, M. D. , Stacey A. Missmer, Sc. D. , Katharine F

Difference between serum beta-human chorionic gonadotropin levels in pregnancies after in vitro maturation and in vitro fertilization treatments Benny.

Are endometrial parameters by three-dimensional ultrasound and power Doppler angiography related to in vitro fertilization/embryo transfer outcome? Luis.

A mandatory single blastocyst transfer policy with educational campaign in a United States IVF program reduces multiple gestation rates without sacrificing.

Reducing the dose of human chorionic gonadotropin in high responders does not affect the outcomes of in vitro fertilization David W. Schmidt, M.D.,,

Chantae Sullivan-Pyke, M. D. , Daniel J. Haisenleder, Ph. D

Impact of subclinical hypothyroidism in women with recurrent early pregnancy loss Lia A. Bernardi, M.D., Ronald N. Cohen, M.D., Mary D. Stephenson, M.D.,

Use of Utrogestan during controlled ovarian hyperstimulation in normally ovulating women undergoing in vitro fertilization or intracytoplasmic sperm injection.

Lapse in embryo transfer training does not negatively affect clinical pregnancy rates for reproductive endocrinology and infertility fellows Jessica.

Eric S. Surrey, M. D. , Debra A. Minjarez, M. D. , John M. Stevens, B

David H. Barad, M.D., M.S., Norbert Gleicher, M.D.

Transfer of two versus three embryos in women less than 40 years old undergoing frozen transfer cycles Inna Berin, M.D., Lawrence L. Engmann, M.D., Claudio.

Krinos M. Trokoudes, M. D. , Constantinos Pavlides, M. Sc

Randomized, controlled pilot trial of natural versus hormone replacement therapy cycles in frozen embryo replacement in vitro fertilization Ginny Mounce,

Logarithmic curves depicting initial level and rise of serum beta human chorionic gonadotropin and live delivery outcomes with in vitro fertilization:

The cumulative probability of liveborn multiples after in vitro fertilization: a cohort study of more than 10,000 women Beth A. Malizia, M.D., Laura.

Hyperglycosylated human chorionic gonadotropin as an early predictor of pregnancy outcomes after in vitro fertilization Sandy Chuan, M.D., Michael Homer,

Not all twins are monozygotic after elective single embryo transfer: analysis of 32,600 elective single embryo transfer cycles as reported to the Society.

Male age negatively impacts embryo development and reproductive outcome in donor oocyte assisted reproductive technology cycles John L. Frattarelli,

Presentation transcript:

Association of the very early rise of human chorionic gonadotropin with adverse outcomes in singleton pregnancies after in vitro fertilization Christopher B. Morse, M.D., Kurt T. Barnhart, M.D., M.S.C.E., Suneeta Senapati, M.D., M.S.C.E., Mary D. Sammel, Sc.D., Erica C. Prochaska, B.A., Anuja Dokras, M.D., Ph.D., Charalampos Chatzicharalampous, M.D., Christos Coutifaris, M.D., Ph.D. Fertility and Sterility Volume 105, Issue 5, Pages 1208-1214.e3 (May 2016) DOI: 10.1016/j.fertnstert.2015.12.141 Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Linear regression of hCG rise versus birth weight in male (blue dots) and female (red x's) infants. There was a significant positive association between hCG rise and birth weight (P=.002; n = 360). Fertility and Sterility 2016 105, 1208-1214.e3DOI: (10.1016/j.fertnstert.2015.12.141) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Linear regression of hCG rise versus birth weight of singleton pregnancies after fresh embryo transfer cycles (red dots) or following frozen/thawed embryo transfer cycles (blue x's). There was a significant positive association between hCG rise and birth weight (P=.002; n = 360). Fertility and Sterility 2016 105, 1208-1214.e3DOI: (10.1016/j.fertnstert.2015.12.141) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 1 Linear regressions of hCG rise versus birth weight of singleton pregnancies after (A) fresh or (B) frozen/thawed embryo transfer cycles. A statistical test for effect modification due to type of transfer (fresh vs. frozen) was not statistically significant (P=.263). Fertility and Sterility 2016 105, 1208-1214.e3DOI: (10.1016/j.fertnstert.2015.12.141) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 2 Box plots of hCG rise after fresh (n = 291) versus frozen/thawed (n = 69) embryo transfer cycles stratified by cutoff points in (A) absolute hCG value and (B) number of days after egg retrieval. *P≤.0001; +P≤.01. Fertility and Sterility 2016 105, 1208-1214.e3DOI: (10.1016/j.fertnstert.2015.12.141) Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions