Pilot Study: Elevated Circulating Levels of the Proinflammatory Cytokine Macrophage Migration Inhibitory Factor in Patients With Chronic Spinal Cord Injury

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Pilot Study: Elevated Circulating Levels of the Proinflammatory Cytokine Macrophage Migration Inhibitory Factor in Patients With Chronic Spinal Cord Injury Adam Stein, MD, Arti Panjwani, DO, Cristina Sison, PhD, Lisa Rosen, ScM, Radhika Chugh, MD, Christine Metz, PhD, Matthew Bank, MD, Ona Bloom, PhD Archives of Physical Medicine and Rehabilitation Volume 94, Issue 8, Pages 1498-1507 (August 2013) DOI: 10.1016/j.apmr.2013.04.004 Copyright © 2013 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 1 MIF levels in plasma of patients with chronic SCI and uninjured control subjects. For each group, thick bar indicates median levels and thin bars indicate IQR. P value indicates Mann-Whitney. P<.001. Archives of Physical Medicine and Rehabilitation 2013 94, 1498-1507DOI: (10.1016/j.apmr.2013.04.004) Copyright © 2013 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 2 Circulating levels of MIG/CXCL9, MCSF, and IL-3 in patients with chronic SCI and uninjured control subjects. (A) MIG/CXCL9, P<.03. (B) MCSF, P<.03. (C) IL-3, P<.04. For each group, thick bar indicates median levels and thin bars indicate IQR. P values indicates Mann-Whitney. Archives of Physical Medicine and Rehabilitation 2013 94, 1498-1507DOI: (10.1016/j.apmr.2013.04.004) Copyright © 2013 American Congress of Rehabilitation Medicine Terms and Conditions

Fig 3 (A) SCGF-β levels in plasma of patients with chronic SCI and uninjured control subjects. Bar indicates median levels in each group. For each group, thick bar indicates median levels and thin bars indicate IQR. (B) Each point represents SCGF-β data from a subject with chronic SCI (Y-axis) plotted according to the years from initial injury for that subject (X-axis). Spearman rho (ρ) correlation coefficient =.469. Archives of Physical Medicine and Rehabilitation 2013 94, 1498-1507DOI: (10.1016/j.apmr.2013.04.004) Copyright © 2013 American Congress of Rehabilitation Medicine Terms and Conditions