E. Losina, S. A. Burbine, L. G. Suter, D. J. Hunter, D. H. Solomon, M

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Pharmacologic regimens for knee osteoarthritis prevention: can they be cost-effective?  E. Losina, S.A. Burbine, L.G. Suter, D.J. Hunter, D.H. Solomon, M.E. Daigle, E.E. Dervan, J.M. Jordan, J.N. Katz  Osteoarthritis and Cartilage  Volume 22, Issue 3, Pages 415-430 (March 2014) DOI: 10.1016/j.joca.2014.01.005 Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Sequence of OA prevention, incidence, and treatment. Osteoarthritis and Cartilage 2014 22, 415-430DOI: (10.1016/j.joca.2014.01.005) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 DMOADs as prevention in the OAPol Model. Osteoarthritis and Cartilage 2014 22, 415-430DOI: (10.1016/j.joca.2014.01.005) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Incremental Cost-effectiveness ratios of DMOADs as prevention: ‘Obese with knee injury’ cohort; prophylaxis with 0.22% major toxicity. Osteoarthritis and Cartilage 2014 22, 415-430DOI: (10.1016/j.joca.2014.01.005) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 Incremental cost-effectiveness ratios of DMOADs as prevention: ‘Knee injury only’ cohort; prophylaxis with 0.22% major toxicity. Osteoarthritis and Cartilage 2014 22, 415-430DOI: (10.1016/j.joca.2014.01.005) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Technical Appendix Fig. 1 Incremental cost-effectiveness ratios of DMOADs for OA prevention: ‘Obese with knee injury’ cohort. Osteoarthritis and Cartilage 2014 22, 415-430DOI: (10.1016/j.joca.2014.01.005) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Technical Appendix Fig. 1 Incremental cost-effectiveness ratios of DMOADs for OA prevention: ‘Obese with knee injury’ cohort. Osteoarthritis and Cartilage 2014 22, 415-430DOI: (10.1016/j.joca.2014.01.005) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Technical Appendix Fig. 2 Incremental cost-effectiveness ratios of DMOADs for OA prevention: ‘Knee injury only’ cohort. Osteoarthritis and Cartilage 2014 22, 415-430DOI: (10.1016/j.joca.2014.01.005) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

Technical Appendix Fig. 2 Incremental cost-effectiveness ratios of DMOADs for OA prevention: ‘Knee injury only’ cohort. Osteoarthritis and Cartilage 2014 22, 415-430DOI: (10.1016/j.joca.2014.01.005) Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions