Fundamentals of Multiscale Fabrication Micro- and nanofluidics

Slides:

Advertisements

Similar presentations

Design and Simulation of a MEMS Piezoelectric Micropump Alarbi Elhashmi, Salah Al-Zghoul, Advisor: Prof. Xingguo Xiong Department of Biomedical Engineering,

Advertisements

The «Lab-On-a-Chip» Concept Initiated in the 1990’s, Lab-On-a-Chip (LOC) technology represents a revolution in laboratory experimentation. The main benefits.

MICROFLEX S Beeby, J Tudor, University of Southampton Introduction to MEMS What is MEMS? What do MEMS devices look like? What can they do? How do we make.

MICROFLUIDIC PUMPS TO BE PRESENTED BY UMAR ABDULLAHI ABDULHAMEED MAY,2013.

Chapter 01: Flows in micro-fluidic systems Xiangyu Hu Technical University of Munich.

Nanotechnology for Electronics and Sensors BIOE298dp ( )

CISMM: Computer Integrated Systems for Microscopy and Manipulation Collaborators: Dr. R. E. Cheney, Dept of Cell and Molecular Physiology Project Lead:

CHE/ME 109 Heat Transfer in Electronics LECTURE 17 – INTERNAL FORCED CONVECTION FUNDAMENTALS.

Sensing and Actuation in Miniaturized Systems Sensing and Actuation in Miniaturized Systems PRESENTATION DNA Transformation by Local Heat Shock

Introduction of Micro- /Nano-fluidic Flow J. L. Lin Assistant Professor Department of Mechanical and Automation Engineering 6/23/

Why Laminar Flow in Narrow Channels (Heat Transfer Analysis)

CHE/ME 109 Heat Transfer in Electronics

Miniaturized Silicon Nanowire System for the In Vivo Diagnosis of Disease R. Myers, L. Rivera, Y. He, Z. Li and J. Villalba.

BGU Physics Department: Going with the (Laminar) Flow

Nanofluid Challenge & its applications

Scale-up and micro reactors. Bench scale achieved desired conversion, yield, selectivity, productivity S2 CHEMICAL REACTION ENGINEERING LABORATORY S7.

Global Microfluidics Market Future Market Insights

BIOMICROFLUIDICS May 12, 2003 Final Report Susan Beatty Stacy Cabrera Saba Choudhary Dan Janiak

BioSensors Yang Yang 9/28/2004. Outlines BioMEMS Enzyme-coated carbon nanotubes Microcantilever biosensor with environmentally responsive hydrogel Cantilever.

Minibioreactors -> Volumes below 100 ml Characterized by: -> area of application -> mass transfer -> mixing characteristics.

Nanofluidic Microsystems for Advanced Biosample Preparation Ying-Chih Wang 1, Jianping Fu, Yong-Ak Song and Jongyoon Han 2,3 1 Department.

Jonathan Ims BME 281 Sec. 1.  1964, Folkman demonstrated a silicon rubber pill for low molecular weight drugs.  1970s, Langer expanded on Folkman ◦

Nanotechnology for Electronics and Sensors BIOE198dp ( )

What is MEMS Technology?. What is MEMS ? What is MEMS ? Micro Electro Mechanical Systems – micro scale dimensions (1mm = 1000 microns) – electrical and.

Chip Lid Molding ENGR Pre Lab. Micro-fabrication  How can we produce devices on a very small scale ?  e.g. Device dimensions 10 nm – 400 µm.

4.2 Notes RESISTANCE IN FLUID SYSTEMS. Resistance in Fluid Systems Drag - the force opposing motion when a solid moves through a fluid Drag occurs only.

Figure 23.1: Comparison between microfluidic and nanofluidic biomolecule separation. (a) In microfluidic device, friction between liquid and the molecule.

© Cambridge University Press 2010 Brian J. Kirby, PhD Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY Powerpoint.

Microfluidics: introduction

On scale effects in composite modeling Larissa Gorbatikh Department of Mechanical Engineering The University of New Mexico Co-Sponsored by the National.

Acellular microfluidic lung on a chip design for gas exchange Introduction Design Methods Conclusions Acknowledgements Mathematical Analysis Integration.

SHINE: S eattle’s H ub for I ndustry-driven N anotechnology E ducation North Seattle College Train the NanoTeacher Workshop July 16, 2014 Lithography 1.

MICROCHANNEL DESIGN ISSUES Susan Beatty Anne Samuel Kunal Thaker.

Pipe flow analysis.

Team: (Left to Right) Zachary Heifferon, Zachary Santagata, Patrick Crilly, Kenneth Bean, Michael Dushkoff, Kevin Cho, Adam Wardas, Harold Paschal (Guide)

Microfluidics and BioMEMS Introduction Sami Franssila & Ville Jokinen.

MICROMACHINING TECHNOLOGY. Introduction Micromachining is used to create parts of size in the order of meters. Materials on a micrometer-scale possess.

Microfluidic generator of sub-10-micron hydrosomes Zhenghao Ding, Lunjun Liu, Gabriel C. Spalding* Physics Department, Illinois Wesleyan University Abstract.

Microfluidics & The Field of Bioengineering

Bharath S. Kattemalalawadi interfacial Science and Surface Engineering Lab (iSSELab) Department of Mechanical Engineering, University of Alberta, Edmonton,

Date of download: 9/18/2016 Copyright © ASME. All rights reserved. From: Droplet Detachment Mechanism in a High-Speed Gaseous Microflow J. Fluids Eng.

14ME404 INTRODUCTION TO MEMS DISCIPLINE ELECTIVE-II Thanking everyone for MEMS as an elective subject Dr.J.S.Senthilkumaar, Professor Mechanical Engineering.

14ME404 INTRODUCTION TO MEMS DISCIPLINE ELECTIVE-II Thanking everyone for MEMS as an elective subject Dr.J.S.Senthilkumaar, Professor Mechanical Engineering.

Lecture 2 Fundamentals of Multiscale Fabrication

Centrifugal Casting of Microfluidic Components With PDMS

Sensera Operations Manager

Lecture 1 Fundamentals of Multiscale Fabrication

Lecture 9 Fundamentals of Multiscale Fabrication Applications I:

Date of download: 10/17/2017 Copyright © ASME. All rights reserved.

Kathryn Rose Verfaillie with Dr. Nivedita Gupta and Brian Zukas

Overview of Issue

Lecture 6 Fundamentals of Multiscale Fabrication

Lecture 7 Fundamentals of Multiscale Fabrication

Date of download: 10/25/2017 Copyright © ASME. All rights reserved.

Lecture 4 Fundamentals of Multiscale Fabrication

Fundamentals of Multiscale Fabrication

A Multiscale Approach to Mesh-based Surface Tension Flows

BME 273 Senior Design Project Group 25

MAE 5130: VISCOUS FLOWS Lecture 1: Introduction and Overview

TURBOMACHINES Chapter 1 INTRODUCTION

CHAPTER 6 Viscous Flow in Pipes

In the past few years, continuous-flow reactors with channel dimensions in the micro- or millimeter region have found widespread application in organic.

Pressure Actuated Valve Test Design

SHAPING PROCESSES FOR PLASTICS

MicroElectroMechanical Systems

Applications and Acknowledgements

SACRAMENTO STATE Geology 103 Sedimentology and Stratigraphy Tim Horner Geology Department, CSU Sacramento Lecture #3: Fundamentals of fluid flow Reading.

3D Staggered Herringbone Micromixer for Biomedical Applications

Chaotic Mixing in Microdroplets

Presentation transcript:

Fundamentals of Multiscale Fabrication Micro- and nanofluidics Lecture 11 Applications III: Micro- and nanofluidics Kahp-Yang Suh Associate Professor SNU MAE sky4u@snu.ac.kr

What is Microfluidics? Microfluidics is a technology which refers to the research and development of micro-scale devices which handle small volumes of fluids (as small as micro-, nano-, pico- and even femtoliter volumes). The devices have dimensions ranging from several millimeters to micrometers ~ the miniaturization of the entire system is not a requirement. Materials for microfluidics Fabrication of microfluidics Microfluidic components

Micro-/nanofluidics ► Micro/nanofluidics aims at investigating and developing miniature device which sense, pump, mix, monitor, and control small volume of fluids. ► Micro/nanofluidics has the potential to revolutionize the process and products that use fluid by high integration with a process.

Figure 1. Downscaling of volumes Micro-/nanofluidics Figure 1. Downscaling of volumes

Microfluidics in nature Biomimetic surface In vivo Surface tension

Nanofluidics in nature EDL overlap Aquaporins Ion channel

Transport at different length scale Nanofluidic toolbox

Basic properties in Microfluidics ► All flow is laminar (no turbulent mixing) ► Surface tension becomes significant ► No inertia effects ► Apparent viscosity increases

Microfluidic channels Variety of shapes and manufacturing techniques, depending on application. Typically laminar due to very small length scales and flow rates.

Laminar Flow in Microfluidic Channels  

Multiscale microfluidic elements

Master fabrication

PDMS mold: wonder material for BioMEMS

PDMS mold

Channel Fabrication – Example

Advantages of Microfluidics

Microfluidic Systems for uTAS

Synthesis with Micro reactor

Drug Delivery Microchip J. Santini and R. Langer, MIT

Drug Delivery Micro Needles

Scaling in Micro-/nanofluidics

Scaling in Micro-/nanofluidics

Scaling in Micro-/nanofluidics

Scaling in Micro-/nanofluidics

Scaling in Micro-/nanofluidics

Scaling in Micro-/nanofluidics

Scaling in Micro-/nanofluidics

Scaling in Micro-/nanofluidics

Scaling in Micro-/nanofluidics