The role of the Panton-Valentine leucocidin toxin in staphylococcal disease: a systematic review and meta-analysis  Dr Laura J Shallcross, MBBS, Ellen.

Slides:



Advertisements
Similar presentations
Crohn's disease Prof Daniel C Baumgart, MD, Prof William J Sandborn, MD The Lancet Volume 380, Issue 9853, Pages (November 2012) DOI: /S (12)
Advertisements

Optimisation of infection prevention and control in acute health care by use of behaviour change: a systematic review  Rachel Edwards, MSc, Esmita Charani,
Volume 384, Issue 9961, Pages (December 2014)
Volume 3, Issue 12, Pages (December 2016)
Pathogenesis of urinary tract infections with normal female anatomy
Volume 6, Issue 7, Pages (July 2005)
Distribution of rotavirus strains and strain-specific effectiveness of the rotavirus vaccine after its introduction: a systematic review and meta-analysis 
UK investments in global infectious disease research 1997–2010: a case study  Michael G Head, PGDip, Joseph R Fitchett, MSc, Mary K Cooke, MSc, Fatima.
Volume 3, Issue 3, Pages (March 2016)
Thank God for Richard Dawkins?
Gram-positive infections: lessons learnt and novel solutions
Predictive value of interferon-γ release assays for incident active tuberculosis: a systematic review and meta-analysis  Molebogeng X Rangaka, MBChB,
Yield of HIV-associated tuberculosis during intensified case finding in resource-limited settings: a systematic review and meta-analysis  Katharina Kranzer,
Brian J Coburn, David J Gerberry, Sally Blower 
WHO's recommendation for surgical skin antisepsis is premature
Meta-analysis of randomised controlled trials
Abdominal lipohypertrophy without insulin injection
Comparative genomics and DNA array-based genotyping of pandemic Staphylococcus aureus strains encoding Panton-Valentine leukocidin  S. Monecke, B. Berger-Bächi,
Infections related to totally implantable venous-access ports
Where does a Staphylococcus aureus vaccine stand?
Molecular characterization of methicillin-resistant Staphylococcus aureus isolated over a 2-year period in a Qatari hospital from multinational patients 
Trends in Pneumonia Hospitalizations in Hennepin County, Minnesota,  
European perspective and update on the management of complicated skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus after.
Underestimate of annual malaria imports to Canada – Author reply
A twin with Cushing's disease
Klebsiella pneumoniae liver abscesses
E. Lindberg, I. Adlerberth, A.E. Wold 
Characteristics and survival of patients with Ebola virus infection, malaria, or both in Sierra Leone: a retrospective cohort study  Matthew Waxman, MD,
Clinical impact of antibiotic-resistant Gram-positive pathogens
European perspective and update on the management of complicated skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus after.
Clinical application of oocyte vitrification: a systematic review and meta-analysis of randomized controlled trials  Ana Cobo, Ph.D., César Diaz, M.D. 
Diabetes and risk of physical disability in adults: a systematic review and meta-analysis  Dr Evelyn Wong, MBBS, Kathryn Backholer, PhD, Emma Gearon, BBioMedSc,
How to evaluate and predict the ecologic impact of antibiotics: the pharmaceutical industry view from research and development  R. Bax  Clinical Microbiology.
Trends in virological and clinical outcomes in individuals with HIV-1 infection and virological failure of drugs from three antiretroviral drug classes:
Gene therapy—where are we?
Organisation of the care of patients with heart failure
Volume 379, Issue 9814, Pages (February 2012)
Paediatric mortality related to pandemic influenza A H1N1 infection in England: an observational population-based study  Nabihah Sachedina, MBBS, Prof.
Challenges to eliminate rabies virus infection in China by 2020
Prevalence of tuberculosis, hepatitis C virus, and HIV in homeless people: a systematic review and meta-analysis  Ulla Beijer, PhD, Achim Wolf, MSc, Dr.
Resuscitation at birth and cognition at 8 years of age: a cohort study
Emergence and control of an outbreak of infections due to Panton-Valentine leukocidin positive, ST22 methicillin-resistant Staphylococcus aureus in a.
UK investments in global infectious disease research 1997–2010: a case study  Michael G Head, PGDip, Joseph R Fitchett, MSc, Mary K Cooke, MSc, Fatima.
Cephalosporins: a pharmacological update
Volume 16, Issue 1, Pages (January 2017)
D. Esel, B. Sümerkan, S. Kocagöz  Clinical Microbiology and Infection 
Comparison of sputum collection methods for tuberculosis diagnosis: a systematic review and pairwise and network meta-analysis  Dr Sumona Datta, MD, Lena.
Comparative genomics and DNA array-based genotyping of pandemic Staphylococcus aureus strains encoding Panton-Valentine leukocidin  S. Monecke, B. Berger-Bächi,
Pre-entry screening programmes for tuberculosis in migrants to low-incidence countries: a systematic review and meta-analysis  Dr Robert W Aldridge, MSc,
M. Aires-de-Sousa  Clinical Microbiology and Infection 
Recent developments in staphylococcal scalded skin syndrome
Volume 391, Issue 10117, Pages (January 2018)
A.W. Karchmer  Clinical Microbiology and Infection 
Thank God for Richard Dawkins?
P.M. Hawkey  Clinical Microbiology and Infection 
Diagnosis of tuberculous meningitis with invasive pulmonary sampling
The Lancet Respiratory Medicine
Sequential time to positivity of blood cultures can be a predictor of prognosis of patients with persistent Staphylococcus aureus bacteraemia  M.-S. Hsu,
Volume 392, Issue 10160, Pages (November 2018)
G.M. Rossolini, E. Mantengoli  Clinical Microbiology and Infection 
Antimicrobial resistance among migrants in Europe: a systematic review and meta- analysis  Laura B Nellums, PhD, Hayley Thompson, MPH, Prof Alison Holmes,
Procalcitonin as a diagnostic marker for sepsis
Rise and subsequent decline of community-associated methicillin resistant Staphylococcus aureus ST30-IVc in Copenhagen, Denmark through an effective search.
Infections related to totally implantable venous-access ports
Abstracts Clinical Microbiology and Infection
Serum antibodies against Panton–Valentine leukocidin in a normal population and during Staphylococcus aureus infection  M. Croze, O. Dauwalder, O. Dumitrescu,
J. Wilson, S. Elgohari, D. M. Livermore, B. Cookson, A. Johnson, T
B.A. Cunha  Clinical Microbiology and Infection 
G.C. Schito  Clinical Microbiology and Infection 
A disease of the osteoblast
Presentation transcript:

The role of the Panton-Valentine leucocidin toxin in staphylococcal disease: a systematic review and meta-analysis  Dr Laura J Shallcross, MBBS, Ellen Fragaszy, MSc, Prof Anne M Johnson, MD, Andrew C Hayward, MD  The Lancet Infectious Diseases  Volume 13, Issue 1, Pages 43-54 (January 2013) DOI: 10.1016/S1473-3099(12)70238-4 Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 1 Study selection The Lancet Infectious Diseases 2013 13, 43-54DOI: (10.1016/S1473-3099(12)70238-4) Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 2 Fixed-effects meta-analysis comparing the odds of infection with Panton-Valentine leucocidin-producing strain for Staphylococcus aureus pneumonia versus skin and soft-tissue disease OR=odds ratio The Lancet Infectious Diseases 2013 13, 43-54DOI: (10.1016/S1473-3099(12)70238-4) Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 3 Random-effects meta-analysis comparing the odds of infection with a Panton-Valentine leucocidin-producing strain for Staphylococcus aureus musculoskeletal disease versus skin and soft-tissue infection OR=odds ratio. The Lancet Infectious Diseases 2013 13, 43-54DOI: (10.1016/S1473-3099(12)70238-4) Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 4 Fixed-effects meta-analysis comparing the odds of infection with a Panton-Valentine leucocidin-producing strain for Staphylococcus aureus bacteraemia versus skin and soft-tissue disease OR=odds ratio. The Lancet Infectious Diseases 2013 13, 43-54DOI: (10.1016/S1473-3099(12)70238-4) Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 5 Fixed-effects meta-analysis comparing the odds of infection with a Panton-Valentine leucocidin-producing strain for Staphylococcus aureus abscesses or furuncles to all other presentations of S aureus disease OR=odds ratio. The Lancet Infectious Diseases 2013 13, 43-54DOI: (10.1016/S1473-3099(12)70238-4) Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 6 Random-effects meta-analysis comparing the odds of colonisation with Panton-Valentine leucocidin-producing Staphylococcus aureus versus Panton-Valentine leucocidin-positive skin and soft-tissue infection OR=odds ratio. The Lancet Infectious Diseases 2013 13, 43-54DOI: (10.1016/S1473-3099(12)70238-4) Copyright © 2013 Elsevier Ltd Terms and Conditions

Figure 7 Clinical iceberg of Panton-Valentine leucocidin-associated infection The Lancet Infectious Diseases 2013 13, 43-54DOI: (10.1016/S1473-3099(12)70238-4) Copyright © 2013 Elsevier Ltd Terms and Conditions

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2025 SlidePlayer.com. Inc. All rights reserved.