ITV-Based Robust Optimization for VMAT Planning of Stereotactic Body Radiation Therapy of Lung Cancer Xiaoying Liang, PhD, Dandan Zheng, PhD, Maria Mamalui-Hunter,

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ITV-Based Robust Optimization for VMAT Planning of Stereotactic Body Radiation Therapy of Lung Cancer Xiaoying Liang, PhD, Dandan Zheng, PhD, Maria Mamalui-Hunter, PhD, Stella Flampouri, PhD, Bradford S. Hoppe, MD, MPH, Nancy Mendenhall, MD, Zuofeng Li, DSc Practical Radiation Oncology Volume 9, Issue 1, Pages 38-48 (January 2019) DOI: 10.1016/j.prro.2018.08.005 Copyright © 2018 American Society for Radiation Oncology Terms and Conditions

Figure 1 Axial view of CIRS phantom. Practical Radiation Oncology 2019 9, 38-48DOI: (10.1016/j.prro.2018.08.005) Copyright © 2018 American Society for Radiation Oncology Terms and Conditions

Figure 2 Example of isodose distribution and dose-volume histogram comparison of internal target volume– and planning target volume–based plans. Practical Radiation Oncology 2019 9, 38-48DOI: (10.1016/j.prro.2018.08.005) Copyright © 2018 American Society for Radiation Oncology Terms and Conditions

Figure 3 Relative dose reductions in various normal lung tissue dose-volume parameters in internal target volume–based plans compared with corresponding planning target volume–based plans in phantom study. Practical Radiation Oncology 2019 9, 38-48DOI: (10.1016/j.prro.2018.08.005) Copyright © 2018 American Society for Radiation Oncology Terms and Conditions

Figure 4 Relative integral dose and dose spillage reductions in internal planning target volume–based plans compared with planning target volume–based plans in phantom study. Practical Radiation Oncology 2019 9, 38-48DOI: (10.1016/j.prro.2018.08.005) Copyright © 2018 American Society for Radiation Oncology Terms and Conditions

Figure 5 Normal lung tissue dose reduction and body dose spillage reduction in internal target volume–based plans compared with planning target volume–based plans for patient cases. Practical Radiation Oncology 2019 9, 38-48DOI: (10.1016/j.prro.2018.08.005) Copyright © 2018 American Society for Radiation Oncology Terms and Conditions