Non–hepatitis virus associated mixed essential cryoglobulinemia

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Presentation transcript:

Non–hepatitis virus associated mixed essential cryoglobulinemia Nicholas M.P. Annear, H. Terence Cook, Mark Atkins, Charles D. Pusey, Alan D. Salama Kidney International Volume 77, Issue 2, Pages 161-164 (January 2010) DOI: 10.1038/ki.2009.416 Copyright © 2010 International Society of Nephrology Terms and Conditions

Figure 1 Renal biopsy taken at the time of presentation after treatment of the urinary tract infection. (a) Glomerulus showing global hypercellularity (hematoxylin and eosin staining (H&E)). (b) Periodic acid-Schiff stain highlights the presence of mononuclear cells within capillary lumens. (c) Artery showing fibrinoid necrosis (H&E); original magnification × 400 Kidney International 2010 77, 161-164DOI: (10.1038/ki.2009.416) Copyright © 2010 International Society of Nephrology Terms and Conditions

Figure 2 Biochemical and serological response to therapy. The improvement in serum creatinine, reduction in cryoglobulin levels, and increase in circulating C4 are all shown. These changes have persisted despite subsequent reconstitution of her circulating B cells. Kidney International 2010 77, 161-164DOI: (10.1038/ki.2009.416) Copyright © 2010 International Society of Nephrology Terms and Conditions