Current, Emerging, and Anticipated Therapies for Sickle Cell Disease

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Current, Emerging, and Anticipated Therapies for Sickle Cell Disease Karl A. Nath, MBChB  Mayo Clinic Proceedings  Volume 93, Issue 12, Pages 1703-1706 (December 2018) DOI: 10.1016/j.mayocp.2018.10.010 Copyright © 2018 Terms and Conditions

Figure Major pathobiological processes in sickle cell disease. See text for discussion. DeoxyHbS = deoxygenated hemoglobin S; HbS = hemoglobin S; NO = nitric oxide; pO2 = partial pressure of oxygen; RBC = red blood cell; WBC = white blood cell. Adapted from Nat Rev Nephrol,8 with permission. Mayo Clinic Proceedings 2018 93, 1703-1706DOI: (10.1016/j.mayocp.2018.10.010) Copyright © 2018 Terms and Conditions