Juxtaluminal hypoechoic area in ultrasonic images of carotid plaques and hemispheric symptoms  Maura B. Griffin, MSc, DIC, PhD, Efthyvoulous Kyriacou,

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Juxtaluminal hypoechoic area in ultrasonic images of carotid plaques and hemispheric symptoms  Maura B. Griffin, MSc, DIC, PhD, Efthyvoulous Kyriacou, BSc, PhD, Costas Pattichis, PhD, Dawn Bond, MA, Stavros K. Kakkos, MD, MSc, DIC, PhD, Michael Sabetai, MD, FRCS, PhD, George Geroulakos, MD, PhD, Niki Georgiou, RN, Caroline J. Doré, BSc, Andrew Nicolaides, MS, FRCS, PhD (Hon)  Journal of Vascular Surgery  Volume 52, Issue 1, Pages 69-76 (July 2010) DOI: 10.1016/j.jvs.2010.02.265 Copyright © 2010 Society for Vascular Surgery Terms and Conditions

Fig 1 For image normalization a sample of “blood” free of noise and a sample from the inner two-fourths of the brightest part of the adventitia adjacent to the plaque are obtained. Journal of Vascular Surgery 2010 52, 69-76DOI: (10.1016/j.jvs.2010.02.265) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

Fig 2 A, Plaque with a juxtaluminal black area outlined in red without a visible echogenic cap, which is 10.5 mm2 (JBA + ve ie ≥ 8 mm2) B, Plaque with a juxtaluminal black area without a visible echogenic cap outlined in red, which is 3.2 mm2 (JBA - ve ie < 8 mm2). Journal of Vascular Surgery 2010 52, 69-76DOI: (10.1016/j.jvs.2010.02.265) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

Fig 3 Receiver operator characteristic (ROC) curves for juxtaluminal black area (JBA) and gray-scale median (GSM) showing different diagnostic cut-off points in relation to symptomatic plaques. JBA 8 mm2 provides a sensitivity of 71% and specificity of 67%. For GSM, 15 sensitivity is 71% and specificity is 63%. Journal of Vascular Surgery 2010 52, 69-76DOI: (10.1016/j.jvs.2010.02.265) Copyright © 2010 Society for Vascular Surgery Terms and Conditions