Volume 45, Issue 4, Pages (April 1964)

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Volume 45, Issue 4, Pages 436-439 (April 1964) Primary Reticulum Cell Sarcoma of the Lung with Endobronchial Involvement MILTON B. KRESS, M.D., F.C.C.P. Diseases of the Chest Volume 45, Issue 4, Pages 436-439 (April 1964) DOI: 10.1378/chest.45.4.436 Copyright © 1964 The American College of Chest Physicians Terms and Conditions

FIGURE 1A January 6, 1961, pneumonic process left mid-lung, lower lobe. Diseases of the Chest 1964 45, 436-439DOI: (10.1378/chest.45.4.436) Copyright © 1964 The American College of Chest Physicians Terms and Conditions

FIGURE 1B January 24, 1961, pleural effusion obscuring pneumonic process, cardiac shadow enlarged due to pericardial effusion. Diseases of the Chest 1964 45, 436-439DOI: (10.1378/chest.45.4.436) Copyright © 1964 The American College of Chest Physicians Terms and Conditions

FIGURE 1C February 8, 1961, clearing of pleural effusion, pneumonic process and reduction in cardiac size to normal after nitrogen mustard therapy. Diseases of the Chest 1964 45, 436-439DOI: (10.1378/chest.45.4.436) Copyright © 1964 The American College of Chest Physicians Terms and Conditions

FIGURE 1D April 1, 1961, symmetrically enlarged mediastinal shadow with insignificant changes in the parenchymal infiltration, left upper and mid-lung. Diseases of the Chest 1964 45, 436-439DOI: (10.1378/chest.45.4.436) Copyright © 1964 The American College of Chest Physicians Terms and Conditions

FIGURE 1E April 26, 1961, decrease in mediastinal enlargement to normal after x-ray therapy. Diseases of the Chest 1964 45, 436-439DOI: (10.1378/chest.45.4.436) Copyright © 1964 The American College of Chest Physicians Terms and Conditions

FIGURE 2 (January 2, 1961) Cytologic examination of cells from sputum stained with Papanicolaou stain showing malignant cells compatible with either small cell carcinoma or lymphoma. The loose and individual arrangement strongly suggest a lymphoma. The criteria for malignancy are a high nucleo-cytoplasmic ratio, chromatin clumping and abnormal pattern, prominent and irregular nucleoli, and nuclear molding (x1000). Diseases of the Chest 1964 45, 436-439DOI: (10.1378/chest.45.4.436) Copyright © 1964 The American College of Chest Physicians Terms and Conditions

FIGURE 3A (January 31, 1961) Hematoxylin and eosin stain of section of bronchial biopsy diagnosed as reticulum cell sarcoma (x400). Diseases of the Chest 1964 45, 436-439DOI: (10.1378/chest.45.4.436) Copyright © 1964 The American College of Chest Physicians Terms and Conditions

FIGURE 3B (January 31, 1961) Silver methenamine stain showing marked proliferation of reticulum fibers with cells attached to fibers resembling “pussy willows” (x400). Diseases of the Chest 1964 45, 436-439DOI: (10.1378/chest.45.4.436) Copyright © 1964 The American College of Chest Physicians Terms and Conditions