Mycobacterial Lipid Logic

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Mycobacterial Lipid Logic M. Sloan Siegrist, Carolyn R. Bertozzi  Cell Host & Microbe  Volume 15, Issue 1, Pages 1-2 (January 2014) DOI: 10.1016/j.chom.2013.12.005 Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 1 Mycobacterial Cell Wall Lipids Modulate Macrophage Composition at the Earliest Sites of Infection PDIM suppresses the recruitment of microbicidal, iNOS-positive macrophages by inhibiting TLR signaling, while PGL stimulates the recruitment of more permissive, iNOS-negative macrophages via the CCR2 pathway. Cell Host & Microbe 2014 15, 1-2DOI: (10.1016/j.chom.2013.12.005) Copyright © 2014 Elsevier Inc. Terms and Conditions