Lung deposition of inhaled tobramycin with eFlow rapid/LC Plus jet nebuliser in healthy and cystic fibrosis subjects  Warren Lenney, Frank Edenborough,

Slides:



Advertisements
Similar presentations
Cheryl Cameron, Mark W. Lodes, William M. Gershan 
Advertisements

The prevalence of “risky behaviour” in adults with cystic fibrosis
Safety of inhaled (Tobi®) and intravenous tobramycin in young children with cystic fibrosis  Stefanie Hennig, Karen McKay, Suzanna Vidmar, Katie O'Brien,
R. Roberts, L. Speight, J. Lee, L. George, R. I. Ketchell, D. Lau, J
How does heart rate recovery after sub-maximal exercise correlate with maximal exercise testing in children with CF?  Sarah P. Cohen, David M. Orenstein 
Scott D. Sagel, Marci K. Sontag, Meg M
Megan R. Nelson, Craig R. Adamski, Audrey Tluczek 
Patrick O. Sobande, James D. Acton, Raouf S. Amin, Jeanne Weiland 
Urinary incontinence in 9���16��year olds with cystic fibrosis compared to other respiratory conditions and a normal group  W.J. Browne, C.J. Wood, M.
Measures of body habitus are associated with lung function in adults with cystic fibrosis: A population-based study  Doug L. Forrester, Alan J. Knox,
Laura Viviani, Baroukh M. Assael, Eitan Kerem 
Cirrhosis and other liver disease in cystic fibrosis
Katelyn Krivchenia, Don Hayes, Joseph D. Tobias, Dmitry Tumin 
John Widger, Sarath Ranganathan, Philip J. Robinson 
Computed tomography correlates with improvement with ivacaftor in cystic fibrosis patients with G551D mutation  Shahid I. Sheikh, Frederick R. Long, Karen.
Controlled clinical trials in cystic fibrosis — are we doing better?
Adherence to nebulised therapies in adolescents with cystic fibrosis is best on week- days during school term-time  Rosemary Ball, Kevin W. Southern, Pamela.
Long-term azitromycin treatment of cystic fibrosis patients with chronic Pseudomonas aeruginosa infection; an observational cohort study  Christine Rønne.
Anju Anand, Elizabeth Tullis, Anne Stephenson, Preyanka Abhyankar 
D. Stevens, P.J. Oades, N. Armstrong, C.A. Williams 
Claire J. Tipping, Rebecca L. Scholes, Narelle S. Cox 
Cystic fibrosis mortality trend in Italy from 1970 to 2011
Claire Keating, Armeen D
Long-term daily high and low doses of azithromycin in children with cystic fibrosis: A randomized controlled trial  S.K. Kabra, R. Pawaiya, Rakesh Lodha,
Gerd Döring, Patrick Flume, Harry Heijerman, J. Stuart Elborn 
Amyloidosis in cystic fibrosis: A case series
Laurent Vecellio, Mohamed E
Rajeev Soni, Catherine J. Dobbin, Maree A. Milross, Iven H
Aukje C. Bos, Kimberly M. Passé, Johan W. Mouton, Hettie M
A.H. Gifford  Journal of Cystic Fibrosis 
Effectiveness of inhaled tobramycin in eradicating Pseudomonas aeruginosa in children with cystic fibrosis  Sanja Stanojevic, Valerie Waters, Joseph L.
Inhalation solutions — Which ones may be mixed
E. Tschiedel, H. Grasemann, F. Ratjen  Journal of Cystic Fibrosis 
Colon Cancer in Cystic Fibrosis patients: Is this a growing problem?
Sally H. Pattison, Geraint B. Rogers, Martin Crockard, J
Prevalence and risk factors for recovery of filamentous fungi in individuals with cystic fibrosis  Christopher R. Sudfeld, Elliott C. Dasenbrook, William.
Cytokine gene polymorphisms and severity of CF lung disease
Nasal polyposis in lung transplant recipients with cystic fibrosis
Elliott C. Dasenbrook, Gregory S. Sawicki  Journal of Cystic Fibrosis 
Narelle S. Cox, Jennifer Follett, Karen O. McKay 
Chee Y. Ooi, Peter R. Durie  Journal of Cystic Fibrosis 
Novel concepts in evaluating antimicrobial therapy for bacterial lung infections in patients with cystic fibrosis  Geraint B. Rogers, Lucas R. Hoffman,
Nutritional decline in cystic fibrosis related diabetes: The effect of intensive nutritional intervention  H. White, K. Pollard, C. Etherington, I. Clifton,
Respiratory pathogens mediate the association between lung function and temperature in cystic fibrosis  Joseph M. Collaco, Karen S. Raraigh, Lawrence.
Trends in pathogens colonising the respiratory tract of adult patients with cystic fibrosis, 1985–2005  F.A. Millar, N.J. Simmonds, M.E. Hodson  Journal.
F. Vermeulen, P. Lebecque, K. De Boeck, T. Leal 
V. Thompson, N. Mayer-Hamblett, M. Kloster, D. Bilton, P.A. Flume 
Diabetes mellitus and survival in cystic fibrosis patients after lung transplantation  Markus Hofer, Christoph Schmid, Christian Benden, Rudolf Speich,
H. White, A.M. Morton, S.P. Conway, D.G. Peckham 
J.E. Spahr, R.B. Love, M. Francois, K. Radford, K.C. Meyer 
James H. Hull, Rachel Garrod, Timothy B. Ho, Ronald K. Knight, John R
Daniel J. Smith, Gregory J. Anderson, Scott C. Bell, David W. Reid 
D.F. Waterhouse, A.M. McLaughlin, C.G. Gallagher 
The role of respiratory viruses in adult patients with cystic fibrosis receiving intravenous antibiotics for a pulmonary exacerbation  C. Etherington,
Gut dysbiosis in cystic fibrosis
CFTR modulators and pregnancy: Our work has only just begun
‘Peeling paint’ dermatitis as a presenting sign of cystic fibrosis
L. Nshimyumukiza, A. Bois, P. Daigneault, L. Lands, A. -M. Laberge, D
Cheryl Cameron, Mark W. Lodes, William M. Gershan 
Lutz Goldbeck, Sven Zerrer, Tim G. Schmitz  Journal of Cystic Fibrosis 
Khin M. Gyi, Margaret E. Hodson, Magdi Y. Yacoub 
David Adeboyeku, Sandra Scott, Margaret E. Hodson 
Elisabeth P. Dellon, Margaret W. Leigh, James R. Yankaskas, Terry L
Anne K. Swisher, Kathryn Moffett, Linda Baer 
Inhaled amiloride and tobramycin solutions fail to eradicate Burkholderia dolosa in patients with cystic fibrosis  Ahmet Z. Uluer, David A. Waltz, Leslie.
Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: The EAGER trial  Michael W. Konstan, Patrick A. Flume, Matthias.
Population pharmacokinetics of tobramycin administered thrice daily and once daily in children and adults with cystic fibrosis  D.J. Touw, A.J. Knox,
Safety assessment of inhaled xylitol in subjects with cystic fibrosis
Early aggressive eradication therapy for intermittent Pseudomonas aeruginosa airway colonization in cystic fibrosis patients: 15 years experience  C.R.
Respiratory physicians and clinic coordinators' attitudes to population-based cystic fibrosis carrier screening  Fiona Cunningham, Sharon Lewis, Lisette.
Presentation transcript:

Lung deposition of inhaled tobramycin with eFlow rapid/LC Plus jet nebuliser in healthy and cystic fibrosis subjects  Warren Lenney, Frank Edenborough, Pearl Kho, John M. Kovarik  Journal of Cystic Fibrosis  Volume 10, Issue 1, Pages 9-14 (January 2011) DOI: 10.1016/j.jcf.2010.08.019 Copyright © 2010 European Cystic Fibrosis Society. Terms and Conditions

Fig. 1 Activity distribution of radiolabelled tobramycin in lung regions. Six lung-shaped regions: regions 1–4=mainly large conducting airways; regions 5 and 6=mainly small airways and alveoli. Adapted from Newman et al. [13]. Journal of Cystic Fibrosis 2011 10, 9-14DOI: (10.1016/j.jcf.2010.08.019) Copyright © 2010 European Cystic Fibrosis Society. Terms and Conditions