Michael Copland, MD, Paul Komenda, MD, Eric D

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Intensive Hemodialysis, Mineral and Bone Disorder, and Phosphate Binder Use  Michael Copland, MD, Paul Komenda, MD, Eric D. Weinhandl, PhD, MS, Peter A. McCullough, MD, MPH, Jose A. Morfin, MD  American Journal of Kidney Diseases  Volume 68, Issue 5, Pages S24-S32 (November 2016) DOI: 10.1053/j.ajkd.2016.05.024 Copyright © 2016 National Kidney Foundation, Inc. Terms and Conditions

Figure 1 Distribution of 3-month mean serum phosphorus levels in the Dialysis Outcomes and Practice Patterns Study Practice Monitor, December 2015.10 American Journal of Kidney Diseases 2016 68, S24-S32DOI: (10.1053/j.ajkd.2016.05.024) Copyright © 2016 National Kidney Foundation, Inc. Terms and Conditions

Figure 2 Medicare Part D gross costs per patient-year for phosphate binders, by dialysis provider organization or class, 2011. Abbreviations: DCI, Dialysis Clinic, Inc; FDF, free-standing dialysis facility; HDF, hospital-based dialysis facility; SDO, small dialysis organization. American Journal of Kidney Diseases 2016 68, S24-S32DOI: (10.1053/j.ajkd.2016.05.024) Copyright © 2016 National Kidney Foundation, Inc. Terms and Conditions

Figure 3 Effects of intensive versus conventional hemodialysis on serum phosphorus levels in the Frequent Hemodialysis Network (FHN) Daily Trial,35 FHN Nocturnal Trial,35 and Canadian trial of nocturnal hemodialysis.36 Estimated treatment effects (solid dots) and associated 95% confidence intervals (solid lines) are displayed at the bottom. American Journal of Kidney Diseases 2016 68, S24-S32DOI: (10.1053/j.ajkd.2016.05.024) Copyright © 2016 National Kidney Foundation, Inc. Terms and Conditions

Figure 4 Mean equivalent phosphorus binding dose for intensive versus conventional hemodialysis in the Frequent Hemodialysis Network (FHN) Daily Trial.35 Dashed bars span 1 standard deviation above and below the mean. American Journal of Kidney Diseases 2016 68, S24-S32DOI: (10.1053/j.ajkd.2016.05.024) Copyright © 2016 National Kidney Foundation, Inc. Terms and Conditions

Figure 5 Distribution of equivalent phosphorus binding dose (EQBD) for intensive versus conventional hemodialysis in the Frequent Hemodialysis Network (FHN) Nocturnal Trial.35 American Journal of Kidney Diseases 2016 68, S24-S32DOI: (10.1053/j.ajkd.2016.05.024) Copyright © 2016 National Kidney Foundation, Inc. Terms and Conditions