Breaking the Barrier: Host Cell Invasion by Lujo Virus Stefan Kunz, Juan Carlos de la Torre Cell Host & Microbe Volume 22, Issue 5, Pages 583-585 (November 2017) DOI: 10.1016/j.chom.2017.10.014 Copyright © 2017 Elsevier Inc. Terms and Conditions
Figure 1 LUJV Cell Entry Interaction at the cell surface between LUJV GP1 and NRP2 mediates LUJV endocytosis. The acidic environment of the late endosome promotes dissociation of the trimeric GP1 from NRP2, which allows the late endosome resident protein CD63 to trigger fusion between the viral membrane and the limiting membrane of the late endosome. Cell Host & Microbe 2017 22, 583-585DOI: (10.1016/j.chom.2017.10.014) Copyright © 2017 Elsevier Inc. Terms and Conditions