Physics and Imaging in Radiation Oncology

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Presentation transcript:

Physics and Imaging in Radiation Oncology A case-control study using motion-inclusive spatial dose-volume metrics to account for genito-urinary toxicity following high-precision radiotherapy for prostate cancer Oscar Casares-Magaz, Ludvig P. Muren, Niclas Pettersson, Maria Thor, Austin Hopper, Rick Knopp, Joseph O. Deasy, Michael Væth, John Einck, Vitali Moiseenko Physics and Imaging in Radiation Oncology Volume 7, Pages 65-69 (July 2018) DOI: 10.1016/j.phro.2018.09.005 Copyright © 2018 The Authors Terms and Conditions

Physics and Imaging in Radiation Oncology 2018 7, 65-69DOI: (10.1016/j.phro.2018.09.005) Copyright © 2018 The Authors Terms and Conditions

Fig. 1 Planned (left), delivered fractions (middle) and weighted average delivered (right) DVHs in absolute volume for cases (red) and controls (black). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.) Physics and Imaging in Radiation Oncology 2018 7, 65-69DOI: (10.1016/j.phro.2018.09.005) Copyright © 2018 The Authors Terms and Conditions

Fig. 2 Mean differences in the weighted average DVH metrics (absolute volume) between cases and controls for the bladder shell and subsectors of the inferior part of the bladder shell. None of these differences were significant. Physics and Imaging in Radiation Oncology 2018 7, 65-69DOI: (10.1016/j.phro.2018.09.005) Copyright © 2018 The Authors Terms and Conditions

Fig. 3 Left panel: box plot for delivered bladder volume at each CBCT and bladder volumes at the planning CT (red squares) for both groups. Middle panel: box plot for planned and weighted average delivered bladder volumes in cases controls. Right panel: box plot for the difference between weighted average bladder volume and planned. * indicates significant differences, p-value <0.05. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.) Physics and Imaging in Radiation Oncology 2018 7, 65-69DOI: (10.1016/j.phro.2018.09.005) Copyright © 2018 The Authors Terms and Conditions