Computational fluid dynamic simulations for determination of ventricular workload in aortic arch obstructions Jessica S. Coogan, PhD, Frandics P. Chan,

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Presentation transcript:

Computational fluid dynamic simulations for determination of ventricular workload in aortic arch obstructions Jessica S. Coogan, PhD, Frandics P. Chan, MD, PhD, John F. LaDisa, PhD, Charles A. Taylor, PhD, Frank L. Hanley, MD, Jeffrey A. Feinstein, MD The Journal of Thoracic and Cardiovascular Surgery Volume 145, Issue 2, Pages 489-495.e1 (February 2013) DOI: 10.1016/j.jtcvs.2012.03.051 Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Three-dimensional models for each patient and corresponding body surface area (BSA)-matched control. The Journal of Thoracic and Cardiovascular Surgery 2013 145, 489-495.e1DOI: (10.1016/j.jtcvs.2012.03.051) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 For the coarctation patient and body surface area–matched control, (right) aortic pressure measured at the inlet of the model and the pressure-volume loop of the left ventricle are shown. Left, Pressure and flow at the hiatus are shown. In each graph, results from the body surface area–matched control (normal) are shown with the results from the coarctation patient reflecting each of the different adaptations. The Journal of Thoracic and Cardiovascular Surgery 2013 145, 489-495.e1DOI: (10.1016/j.jtcvs.2012.03.051) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Comparison of the percentage of workload change required to maintain cardiac output for the different types and degrees of aortic obstruction. The Journal of Thoracic and Cardiovascular Surgery 2013 145, 489-495.e1DOI: (10.1016/j.jtcvs.2012.03.051) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions

Figure E1 A, Three-dimensional model with inlet shown in yellow and labeled “A” and outlets shown in blue and labeled “1” to “4”. B, Outlets 1 to 4 are coupled to the Windkessel model. C, Inlet A is coupled to the heart model. Rp, Resistance of proximal, larger vessels; Rd, resistance of distal, smaller vessel; C, capacitance of proximal, larger vessels; PLA, left atrial pressure; RAV, mitral valve resistance; LAV, mitral valve inductance; E(t), left ventricular elastance; RV-Art, aortic valve resistance; LV-Art, aortic valve inductance. The Journal of Thoracic and Cardiovascular Surgery 2013 145, 489-495.e1DOI: (10.1016/j.jtcvs.2012.03.051) Copyright © 2013 The American Association for Thoracic Surgery Terms and Conditions