Metabolic disturbances in non-obese women with polycystic ovary syndrome: a systematic review and meta-analysis Shiqin Zhu, M.D., Bingqian Zhang, M.D.,

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Metabolic disturbances in non-obese women with polycystic ovary syndrome: a systematic review and meta-analysis Shiqin Zhu, M.D., Bingqian Zhang, M.D., Xiao Jiang, M.D., Zeyan Li, M.D., Shigang Zhao, M.D., Ph.D., Linlin Cui, M.D., Ph.D., Zi-Jiang Chen, M.D., Ph.D. Fertility and Sterility Volume 111, Issue 1, Pages 168-177 (January 2019) DOI: 10.1016/j.fertnstert.2018.09.013 Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Flow diagram for study selection. Fertility and Sterility 2019 111, 168-177DOI: (10.1016/j.fertnstert.2018.09.013) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Meta-analysis on insulin resistance (IR), impaired glucose tolerance (IGT), impaired fasting glucose (IFG), and type 2 diabetes mellitus (T2DM): nonobese women with PCOS versus nonobese healthy controls. Forest plot displayed odds of IR (A), IGT (B), IFG (C), and T2DM (D) in nonobese women with PCOS versus nonobese healthy controls. Fertility and Sterility 2019 111, 168-177DOI: (10.1016/j.fertnstert.2018.09.013) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

Figure 3 Forrest plot displayed odds of hypertension and metabolic syndrome (Mets) in nonobese women with PCOS versus nonobese healthy controls. (A) Meta-analysis on hypertension; (B) meta-analysis on Mets. Fertility and Sterility 2019 111, 168-177DOI: (10.1016/j.fertnstert.2018.09.013) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 1 Sensitivity analysis of metabolic syndrome. Fertility and Sterility 2019 111, 168-177DOI: (10.1016/j.fertnstert.2018.09.013) Copyright © 2018 American Society for Reproductive Medicine Terms and Conditions