Identification of Pediatric Patients With Celiac Disease Based on Serology and a Classification and Regression Tree Analysis  Anna Ermarth, Matthew Bryce,

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Presentation transcript:

Identification of Pediatric Patients With Celiac Disease Based on Serology and a Classification and Regression Tree Analysis  Anna Ermarth, Matthew Bryce, Stephanie Woodward, Gregory Stoddard, Linda Book, M. Kyle Jensen  Clinical Gastroenterology and Hepatology  Volume 15, Issue 3, Pages 396-402.e2 (March 2017) DOI: 10.1016/j.cgh.2016.10.035 Copyright © 2017 Terms and Conditions

Figure 1 Prediction of celiac disease using antibodies to TTG-IgA shown by regression curve. CD, celiac disease. Clinical Gastroenterology and Hepatology 2017 15, 396-402.e2DOI: (10.1016/j.cgh.2016.10.035) Copyright © 2017 Terms and Conditions

Figure 2 CART analysis of celiac disease with TTG-IgA antibody level, age, and sex. Clinical Gastroenterology and Hepatology 2017 15, 396-402.e2DOI: (10.1016/j.cgh.2016.10.035) Copyright © 2017 Terms and Conditions

Supplementary Figure 1 ROC curve of TTG-IgA single serology; AUROC = 0.9466. Clinical Gastroenterology and Hepatology 2017 15, 396-402.e2DOI: (10.1016/j.cgh.2016.10.035) Copyright © 2017 Terms and Conditions

Supplementary Figure 2 ROC curve of TTG-IgA + DGP-IgA serology; AUROC = 0.9464. Clinical Gastroenterology and Hepatology 2017 15, 396-402.e2DOI: (10.1016/j.cgh.2016.10.035) Copyright © 2017 Terms and Conditions

Supplementary Figure 3 ROC curve of DGP-IgA single serology; AUROC = 0.6657. Clinical Gastroenterology and Hepatology 2017 15, 396-402.e2DOI: (10.1016/j.cgh.2016.10.035) Copyright © 2017 Terms and Conditions

Supplementary Figure 4 ROC curve of TTG-IgG + DGP-IgG serology; AUROC = 0.5629. Clinical Gastroenterology and Hepatology 2017 15, 396-402.e2DOI: (10.1016/j.cgh.2016.10.035) Copyright © 2017 Terms and Conditions

Supplementary Figure 5 CART analysis of celiac disease with TTG-IgA and type I DM. Clinical Gastroenterology and Hepatology 2017 15, 396-402.e2DOI: (10.1016/j.cgh.2016.10.035) Copyright © 2017 Terms and Conditions

Supplementary Figure 6 CART analysis of celiac disease with TTG-IgA and trisomy 21. Clinical Gastroenterology and Hepatology 2017 15, 396-402.e2DOI: (10.1016/j.cgh.2016.10.035) Copyright © 2017 Terms and Conditions

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