Heterogeneity of hemochromatosis in Italy

Slides:

Advertisements

Similar presentations

Genetic testing for high-risk colon cancer patients1 William M. Grady Gastroenterology Volume 124, Issue 6, Pages (May 2003) DOI: /S (03)

Advertisements

Celiac disease–like abnormalities in a subgroup of patients with irritable bowel syndrome Ulrich Wahnschaffe, R. Ullrich, E.O. Riecken, J.D. Schulzke Gastroenterology.

Serum immunoglobulin a from patients with celiac disease inhibits human T84 intestinal crypt epithelial cell differentiation Tuula Halttunen, Markku Mäki.

It's time to bring the best and brightest back to gastroenterology!

Volume 58, Issue 1, Pages (January 2013)

Andrew B. Rosenkrantz, MD, MPA, James V. Rawson, MD

Metronidazole susceptibility in Helicobacter pylori

Volume 116, Issue 2, Pages (February 1999)

Volume 117, Issue 1, Pages (July 1999)

Maria Eugenia D’Amato, Mohaimin Kasu

E. Svensson, J. Millet, A. Lindqvist, M. Olsson, M. Ridell, N. Rastogi

Volume 122, Issue 3, Pages (March 2002)

Volume 115, Issue 6, Pages (December 1998)

Homozygous deletion of HFE: the Sardinian hemochromatosis?

Diagnosis of irritable bowel syndrome

Is rectal pain sensitivity a biological marker for irritable bowel syndrome: Psychological influences on pain perception William E. Whitehead, Olafur.

Leptin, obesity, and liver disease

Systematic review of the comorbidity of irritable bowel syndrome with other disorders: What are the causes and implications? William E. Whitehead, Olafur.

Gastric cancer, cytotoxin-associated gene A–positive Helicobacter pylori, and serum pepsinogens: An international study Penelope M. Webb, Jean E. Crabtree,

James A. Sliwa, DO, Allen Heinemann, PhD, Patrick Semik, BA

Natural history of the C282Y homozygote for the hemochromatosis gene (HFE) with a normal serum ferritin level Cory Yamashita, Paul C Adams Clinical.

Psychiatric disorders among veterans with hepatitis C infection

A priori probabilities in Y23 mixture analysis: Non-contributor experiments using simulated powerplex® Y23 Y-STR mixtures D. Moore, T. Clayton, J. Thomson

Volume 61, Issue 5, Pages (May 2012)

Metronidazole susceptibility in Helicobacter pylori

Volume 115, Issue 1, Pages (July 1998)

Appendectomy is followed by increased risk of Crohn's disease

Hepatitis B virus genotype B is associated with earlier HBeAg seroconversion compared with hepatitis B virus genotype C Chi–Jen Chu, Munira Hussain,

A novel mutation of HFE explains the classical phenotype of genetic hemochromatosis in a C282Y heterozygote Daniel F. Wallace, James S. Dooley, Ann P.

Volume 120, Issue 3, Pages (February 2001)

Duodenal expression of a putative stimulator of Fe transport and transferrin receptor in anemia and hemochromatosis Donatella Barisani, Dario Conte

Ultrasonography or venography for the diagnosis of TIPS malfunction?

Antje Timmer*, Lloyd R. Sutherland*,‡, Francois Martin§

Volume 122, Issue 5, Pages (May 2002)

The Penetrance of Hemochromatosis: Mice to the Rescue

An evidence-based medicine approach to studies of diagnostic tests: Assessing the validity of virtual colonoscopy Brooks D. Cash, Philip Schoenfeld,

Volume 120, Issue 4, Pages (March 2001)

Epidemiology of opportunistic infections in AIDS patients

Severe Constipation Clinical Gastroenterology and Hepatology

Andrea Mingoli, MD, Paolo Sapienza, MD, Richard J

Volume 119, Issue 2, Pages (August 2000)

Volume 117, Issue 5, Pages (November 1999)

Maria Eugenia D’Amato, Mohaimin Kasu

James E. Everhart, Meena Khare, Michael Hill, Kurt R. Maurer

Volume 137, Issue 4, Pages (October 2009)

Volume 133, Issue 2, Pages (August 2007)

Lise L. Kjaergard, Sarah L. Frederiksen, Christian Gluud

AGA technical review on nonalcoholic fatty liver disease

CPR 1.2.: Evaluation of Anemia in CKD

Psychiatric disorders among veterans with hepatitis C infection

Colorectal cancer at a young age

Worse Outcomes of Patients With HFE Hemochromatosis With Persistent Increases in Transferrin Saturation During Maintenance Therapy Edouard Bardou-Jacquet,

Georgios I. Papachristou, David A

Hemochromatosis: Diagnosis and management

Chronic Diarrhea Clinical Gastroenterology and Hepatology

AGA technical review on osteoporosis in gastrointestinal diseases

Volume 122, Issue 4, Pages (April 2002)

Personalized asthma therapy in blacks—the role of genetic ancestry

Liver transplantation in children

Jia-Horng Kao*, Pei-Jer Chen*, Ming-Yang Lai*, Ding-Shinn Chen‡,§

Hepatitis C Genotypes: Current Trends and Future Implications

Michelle Maria Pietzak Gastroenterology

Table of contents The Journal for Nurse Practitioners

Mammen Chandy Biology of Blood and Marrow Transplantation

Racial Differences in Survival of Hepatocellular Carcinoma in the United States: A Population-Based Study Jessica A. Davila, Hashem B. El–Serag Clinical.

Scott K. Fung, Anna S.F. Lok Clinical Gastroenterology and Hepatology

Should patient age be a consideration in carotid endarterectomy?

Presidential address: The second-generation vascular surgeon

Alice S. Whittemore, Jerry Halpern

Results of a single center vascular screening and education program

Presentation transcript:

Heterogeneity of hemochromatosis in Italy Alberto Piperno*, Maurizio Sampietro‡, Antonello Pietrangelo§, Cristina Arosio*,∥, Loredana Lupica‡, Giuliana Montosi§, Anna Vergani*, Mirella Fraquelli¶, Domenico Girelli#, Paolo Pasquero**, Antonella Roetto**, Paolo Gasparini‡‡, Silvia Fargion‡, Dario Conte¶, Clara Camaschella** Gastroenterology Volume 114, Issue 5, Pages 996-1002 (May 1998) DOI: 10.1016/S0016-5085(98)70319-1 Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 1 Frequency of HFE genotypes in Italian patients with a hemochromatosis phenotype divided according to geographical origin (ascertained up to the third generation). C282Y +/+ genotype: P < 0.0001 between patients of northern and central/southern Italy. Gastroenterology 1998 114, 996-1002DOI: (10.1016/S0016-5085(98)70319-1) Copyright © 1998 American Gastroenterological Association Terms and Conditions

Fig. 2 Distribution of C282Y homozygotes according to ancestral haplotype combinations and phenotype severity (based on the ratio of total IR and age [IR/age]. Class I includes patients with IR/age ≤ 0.33. Class II includes patients with IR/age > 0.33. Gastroenterology 1998 114, 996-1002DOI: (10.1016/S0016-5085(98)70319-1) Copyright © 1998 American Gastroenterological Association Terms and Conditions