Saphenous vein biopsy: A predictor of vein graft failure

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Presentation transcript:

Saphenous vein biopsy: A predictor of vein graft failure Michael L. Marin, MD, Frank J. Veith, MD, Thomas F. Panetta, MD, Ronald E. Gordon, MD, Kurt R. Wengerter, MD, William D. Suggs, MD, Luis Sanchez, MD, Michael K. Parides, MS Journal of Vascular Surgery Volume 18, Issue 3, Pages 407-415 (September 1993) DOI: 10.1016/0741-5214(93)90258-N Copyright © 1993 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 Light micrograph of greater saphenous vein, which contains plate-like deposit of calcium in vein intima (arrowhead). Entire intima of this vein is mildly thickened. (Methylene blue and azure II stain; original magnification × 10.) Journal of Vascular Surgery 1993 18, 407-415DOI: (10.1016/0741-5214(93)90258-N) Copyright © 1993 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Light micrographs of remnant thigh saphenous veins from two patients undergoing femorodistal bypasses. Marked difference can be seen between thickness of combined inner media-intimal layer. (Methylene blue and azure II stain; original magnification × 100.) Journal of Vascular Surgery 1993 18, 407-415DOI: (10.1016/0741-5214(93)90258-N) Copyright © 1993 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 3 Light micrograph of thigh saphenous vein demonstrating intimal spindle-shaped cells (arrowheads). (Methylene blue and azure II stain; original magnification × 250.) Journal of Vascular Surgery 1993 18, 407-415DOI: (10.1016/0741-5214(93)90258-N) Copyright © 1993 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 4 Transmission electron micrograph of intimal spindle-shaped cell from thigh greater saphenous vein. There are few contractile filaments and numerous secretory granules. (Lead citrate, uranyl acetate stain; original magnification × 750.) Journal of Vascular Surgery 1993 18, 407-415DOI: (10.1016/0741-5214(93)90258-N) Copyright © 1993 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 5 Light micrograph of section through a vein graft stenosis. Small lumen (star) and excessive intimal layer (I) typify this lesion. (Methylene blue and azure II, original magnification × 10.) Journal of Vascular Surgery 1993 18, 407-415DOI: (10.1016/0741-5214(93)90258-N) Copyright © 1993 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 6 Electron micrograph of intima of Fig. 5. There are loosely arranged spindle-shaped cells surrounded by amorphous matrix. (Lead citrate, uraynl acetate stain; original magnification × 750.) Journal of Vascular Surgery 1993 18, 407-415DOI: (10.1016/0741-5214(93)90258-N) Copyright © 1993 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions