Figure 3 Overall survival, according to treatment group Figure 3 | Overall survival, according to treatment group. Results from the Radiation Therapy Oncology Group (RTOG) 9802 trial7. All hazard ratios in the analyses of overall survival are for death, and all P values are two-sided. Tick marks indicate censored data. There were too few events among patients without the IDH1 Arg132His mutation to assess the association with treatment. PCV, procarbazine, lomustine and vincristine; RT, radiation therapy. From The New England Journal of Medicine, Buckner, J. C. et al., Radiation plus procarbazine, CCNU, and vincristine in low-grade glioma, 374, 1344–1355. Copyright © (2016) Massachusetts Medical Society. Reprinted with permission from Massachusetts Medical Society. From The New England Journal of Medicine, Buckner, J. C. et al., Radiation plus procarbazine, CCNU, and vincristine in low-grade glioma, 374, 1344–1355. Copyright © (2016) Massachusetts Medical Society. Reprinted with permission from Massachusetts Medical Society. Buckner, J. et al. (2017) Management of diffuse low-grade gliomas in adults — use of molecular diagnostics Nat. Rev. Neurol. doi:10.1038/nrneurol.2017.54