Underestimation of Liver-Related Mortality in the United States

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Slideset on: Asrani SK, Larson JJ, Yawn B, et al. Underestimation of liver-related mortality in the United States. Gastroenterology. 2013;145: Liver.

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Underestimation of Liver-Related Mortality in the United States Sumeet K. Asrani, Joseph J. Larson, Barbara Yawn, Terry M. Therneau, W. Ray Kim Gastroenterology Volume 145, Issue 2, Pages 375-382.e2 (August 2013) DOI: 10.1053/j.gastro.2013.04.005 Copyright © 2013 AGA Institute Terms and Conditions

Figure 1 Liver-related mortality, 2008. Percent of overall liver related deaths in 2008 by the predefined categories (CDC, expanded (exclusive of CDC), viral hepatitis and hepatobiliary) as stratified by race. The sum of all the rates comprises the updated estimate of liver-related mortality by race. Adjusted to US Census 2000 population, only individuals older than 15 years at risk. AA, African American; AI/AN, American Indian and Alaska Native. Gastroenterology 2013 145, 375-382.e2DOI: (10.1053/j.gastro.2013.04.005) Copyright © 2013 AGA Institute Terms and Conditions

Figure 2 Liver-related mortality in the United States, 1979−2008. Separate trend lines for viral hepatitis, liver cancer, and expanded liver (CDC definition and other causes of liver-related mortality) are provided. The updated estimate includes these 3 diagnosis groups. As a comparison, the current CDC estimate is provided (black line). Adjusted to US Census 2000 population, only individuals older than 15 years at risk. Gastroenterology 2013 145, 375-382.e2DOI: (10.1053/j.gastro.2013.04.005) Copyright © 2013 AGA Institute Terms and Conditions

Figure 3 Liver-related deaths by era. Era 1: 1979−1988; era 2: 1989−1998; era 3: 1999−2008. Adjusted rates per 100,000 are provided by category (CDC, expanded [exclusive of CDC], viral hepatitis, and hepatobiliary malignancies). Adjusted to US Census 2000 population, only individuals older than 15 years at risk. Gastroenterology 2013 145, 375-382.e2DOI: (10.1053/j.gastro.2013.04.005) Copyright © 2013 AGA Institute Terms and Conditions

Figure 4 Age-specific death rates (per 100,000 persons) for liver disease-related mortality in 10-year age groups in the United States, 1979−2008. Gastroenterology 2013 145, 375-382.e2DOI: (10.1053/j.gastro.2013.04.005) Copyright © 2013 AGA Institute Terms and Conditions

Figure 5 Age- and sex-adjusted death rates (per 100,000 persons) in Olmsted County, Minnesota vs national estimate, 1999−2008. Adjusted to US Census 2000 population, only individuals older than 15 years at risk. Gastroenterology 2013 145, 375-382.e2DOI: (10.1053/j.gastro.2013.04.005) Copyright © 2013 AGA Institute Terms and Conditions