Priscila Badia, Heidi Andersen, David Haslam, Adam S

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Impact of Xylitol on Oral Microbiome and Blood Stream Infections in HSCT Recipients Priscila Badia, Heidi Andersen, David Haslam, Adam S. Nelson, Javier El-Bietar, Abigail R. Pate, Sara Golkari, Ashley Teusink-Cross, Laura Flesch, Ashely Bedel, Victoria Hickey, Kathi Kramer, Stella M. Davies, Sarat Thikkurissy, Christopher E. Dandoy Biology of Blood and Marrow Transplantation Volume 24, Issue 3, Pages S427-S428 (March 2018) DOI: 10.1016/j.bbmt.2017.12.510 Copyright © 2017 Terms and Conditions

Figure 1 Results from oral exams performed at baseline and weekly for the first 28 post-transplant days in the Standard of Care (SOC) and Xylitol group Biology of Blood and Marrow Transplantation 2018 24, S427-S428DOI: (10.1016/j.bbmt.2017.12.510) Copyright © 2017 Terms and Conditions

Figure 2 Relative Streptococcus mitis/oralis abundance in oral microbiome. (A) Standard of care group (SOC) and Xylitol group post-transplant (B) Xylitol group only at baseline and post-transplant and (C) Standard of care group only at baseline and post-transplant. Biology of Blood and Marrow Transplantation 2018 24, S427-S428DOI: (10.1016/j.bbmt.2017.12.510) Copyright © 2017 Terms and Conditions

Figure 3 Species abundance represented by bubble chart. (A) Standard of care patient with increase Streptococcus abundance post-transplant (B) Xylitol patient with decrease Streptococcus abundance post-transplant. Biology of Blood and Marrow Transplantation 2018 24, S427-S428DOI: (10.1016/j.bbmt.2017.12.510) Copyright © 2017 Terms and Conditions