Intercellular Junctions: Actin the PARt Le Shen, Jerrold R. Turner  Current Biology  Volume 18, Issue 21, Pages R1014-R1017 (November 2008) DOI: 10.1016/j.cub.2008.10.010 Copyright © 2008 Elsevier Ltd Terms and Conditions

Figure 1 Role for Cdc42, Par6, and aPKC in adherens junction maintenance. Model of adherens junction maintenance in wild-type Drosophila epithelium (left). Mutation of Cdc42, Par6, or aPKC (right) leads to a failure of downstream processes, including vesicle scission, and the accumulation of E-cadherin-rich tubular structures that extend from and destabilize the adherens junction. Current Biology 2008 18, R1014-R1017DOI: (10.1016/j.cub.2008.10.010) Copyright © 2008 Elsevier Ltd Terms and Conditions