Fatal Anaphylaxis: Mortality Rate and Risk Factors

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Presentation transcript:

Fatal Anaphylaxis: Mortality Rate and Risk Factors Paul J. Turner, MD, PhD, Elina Jerschow, MD, Thisanayagam Umasunthar, MD, Robert Lin, MD, Dianne E. Campbell, MD, PhD, Robert J. Boyle, MB, ChB, PhD The Journal of Allergy and Clinical Immunology: In Practice Volume 5, Issue 5, Pages 1169-1178 (September 2017) DOI: 10.1016/j.jaip.2017.06.031 Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 1 Estimated rates of fatal drug, food, and venom anaphylaxis compared with other risks for the general population. Reference risks are for the US population, unless otherwise stated. Bars represent the range of estimates from recent population-based studies of fatal anaphylaxis. The Journal of Allergy and Clinical Immunology: In Practice 2017 5, 1169-1178DOI: (10.1016/j.jaip.2017.06.031) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 2 Estimated rates of fatal food and venom anaphylaxis for people with known food allergy or insect venom allergy. Reference risks are for the US population, unless otherwise stated. Data shown for individuals with food allergy are the 95% confidence interval of fatal food anaphylaxis risk, derived from the systematic review of Umasunthar et al.46 Data shown for individuals with insect venom allergy were calculated using the range of estimates from recent population-based studies of fatal venom anaphylaxis, and an estimated 3% population prevalence of insect venom allergy.48 The Journal of Allergy and Clinical Immunology: In Practice 2017 5, 1169-1178DOI: (10.1016/j.jaip.2017.06.031) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions