What is type 1 diabetes? Medicine

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Presentation transcript:

What is type 1 diabetes? Medicine Madhurima R. Chetan, Sally L. Thrower, Parth Narendran  Medicine  Volume 47, Issue 1, Pages 5-9 (January 2019) DOI: 10.1016/j.mpmed.2018.10.006 Copyright © 2018 Terms and Conditions

Figure 1 Location of β-cell proteins targeted by the autoimmune response in T1DM. Medicine 2019 47, 5-9DOI: (10.1016/j.mpmed.2018.10.006) Copyright © 2018 Terms and Conditions

Figure 2 Insulitis: the human islet (centre) is infiltrated by T and B lymphocytes, macrophages and dendtritic cells in type 1 diabetes mellitis. Medicine 2019 47, 5-9DOI: (10.1016/j.mpmed.2018.10.006) Copyright © 2018 Terms and Conditions

Figure 3 Natural history of β-cell loss in T1DM. Medicine 2019 47, 5-9DOI: (10.1016/j.mpmed.2018.10.006) Copyright © 2018 Terms and Conditions

Figure 4 Diagnosis of T1DM in adults. Adapted from National Institute of Health and Care Excellence guidelines.4 Medicine 2019 47, 5-9DOI: (10.1016/j.mpmed.2018.10.006) Copyright © 2018 Terms and Conditions