Gadolinium Update

Gadolinium-Based Contrast Agents Background

Gadolinium-Based Contrast Agents Background (cont)

Basic Structures of Commercially Available GBCAs

GBCAs and NSF

2018 ACR Manual, Version 10.3

Risk Factors for CKD

Gadolinium Use in Renal Impairment ACR and FDA Guidelines

NSF Key Takeaways

GBCA Deposition and Retention in the Brain Background

GBCAs Retention or Deposition?

Are There Clinical Correlates?

GBCA Deposition and Retention FDA Response

Intracranial GBCA Deposition and Retention EMA Response

Summary What is Known About Gd Deposition and Retention?

GBCA Use During Pregnancy

GBCA-Enhanced MRI for Breast Cancer Screening

GBCA Use in Pediatric Populations

Concluding Remarks

Abbreviations