Radiation-Induced Pulmonary Veno-occlusive Disease

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Presentation transcript:

Radiation-Induced Pulmonary Veno-occlusive Disease Mordechai R. Kramer, M.D., F.C.C.P, Marc Estenne, M.D., Ph.D., Neville Berkman, M.B.B.Ch., M.R.C.P, Martine Antoine, M.D., Philippe de Francquen, M.D., Alex Lipski, M.D., Danielle Jacobovitz, M.D., Joel Lafair, M.D. CHEST Volume 104, Issue 4, Pages 1282-1284 (October 1993) DOI: 10.1378/chest.104.4.1282 Copyright © 1993 The American College of Chest Physicians Terms and Conditions

FIGURE 1 Chest radiography of patient showing diffuse alveolar edema and bilateral pleural effusion. CHEST 1993 104, 1282-1284DOI: (10.1378/chest.104.4.1282) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

FIGURE 2 Lung section showing extensive interstitial fibrosis w ith thickening of interalveolar septa. Alveolar spaces are filled with hemosiderin-laden macrophages (top left). Note intimal thickening of venules (bottom) (hematoxylin eosin, × 400). CHEST 1993 104, 1282-1284DOI: (10.1378/chest.104.4.1282) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

FIGURE 3 Section showing a typical venule with intimal proliferation and near obliteration of lumen, (elastin stain, × 400). CHEST 1993 104, 1282-1284DOI: (10.1378/chest.104.4.1282) Copyright © 1993 The American College of Chest Physicians Terms and Conditions