miR-214 as a Key Hub that Controls Cancer Networks: Small Player, Multiple Functions  Elisa Penna, Francesca Orso, Daniela Taverna  Journal of Investigative Dermatology  Volume 135, Issue 4, Pages 960-969 (April 2015) DOI: 10.1038/jid.2014.479 Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Genomic location of human miR-214. miR-214 and miR-199a-2 are 6 kb apart, located inside the 7.9 kb-long noncoding RNA precursor, DNM3os, in intron 14 of the Dynamin-3 (DNM3) gene (1q24.3). miR-3120 overlaps the miR-214 locus but in its complementary strand. Journal of Investigative Dermatology 2015 135, 960-969DOI: (10.1038/jid.2014.479) Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 2 miR-214 controls cancer networks. miR-214 direct target genes and indirect downstream players are shown, together with their multiple functions in tumor cells (different colors). Journal of Investigative Dermatology 2015 135, 960-969DOI: (10.1038/jid.2014.479) Copyright © 2015 The Society for Investigative Dermatology, Inc Terms and Conditions