Socioeconomic status and race as risk factors for cockroach allergen exposure and sensitization in children with asthma Sampson B. Sarpong, MDa, Robert.

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Presentation transcript:

Socioeconomic status and race as risk factors for cockroach allergen exposure and sensitization in children with asthma Sampson B. Sarpong, MDa, Robert G. Hamilton, PhDb, Peyton A. Eggleston, MDa, N.Franklin Adkinson, MDb Journal of Allergy and Clinical Immunology Volume 97, Issue 6, Pages 1393-1401 (June 1996) DOI: 10.1016/S0091-6749(96)70209-9 Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 1 Distribution of cockroach allergen Bla g 1 and Bla g 2 in three locations of homes of 87 children with moderate to severe asthma. The limit of detection of the assay is 0.8 U/gm. Median levels of homes with detectable cockroach allergens are indicated by horizontal bars. Numbers below the dotted line indicate numbers of samples that contained less than 0.8 U/gm of fine settled dust. Journal of Allergy and Clinical Immunology 1996 97, 1393-1401DOI: (10.1016/S0091-6749(96)70209-9) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 2 Rate of cockroach skin sensitivity related to levels of cockroach allergens in bedroom dust samples for Bla g 1 (A) and Bla g 2 (B). Cockroach allergen levels were significantly related to the presence of a positive skin test response (p < 0.001). Journal of Allergy and Clinical Immunology 1996 97, 1393-1401DOI: (10.1016/S0091-6749(96)70209-9) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 2 Rate of cockroach skin sensitivity related to levels of cockroach allergens in bedroom dust samples for Bla g 1 (A) and Bla g 2 (B). Cockroach allergen levels were significantly related to the presence of a positive skin test response (p < 0.001). Journal of Allergy and Clinical Immunology 1996 97, 1393-1401DOI: (10.1016/S0091-6749(96)70209-9) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 3 Cockroach allergen exposure analyzed by the subject’s SES (A), race nested within SES (B), and residence nested within SES (C). SES was significantly associated with exposure (p < 0.001). A significant difference in race was only seen in the middle SES (p < 0.001). Urban versus suburban residence was not significantly different in any of the three SES groups. Journal of Allergy and Clinical Immunology 1996 97, 1393-1401DOI: (10.1016/S0091-6749(96)70209-9) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 3 Cockroach allergen exposure analyzed by the subject’s SES (A), race nested within SES (B), and residence nested within SES (C). SES was significantly associated with exposure (p < 0.001). A significant difference in race was only seen in the middle SES (p < 0.001). Urban versus suburban residence was not significantly different in any of the three SES groups. Journal of Allergy and Clinical Immunology 1996 97, 1393-1401DOI: (10.1016/S0091-6749(96)70209-9) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 3 Cockroach allergen exposure analyzed by the subject’s SES (A), race nested within SES (B), and residence nested within SES (C). SES was significantly associated with exposure (p < 0.001). A significant difference in race was only seen in the middle SES (p < 0.001). Urban versus suburban residence was not significantly different in any of the three SES groups. Journal of Allergy and Clinical Immunology 1996 97, 1393-1401DOI: (10.1016/S0091-6749(96)70209-9) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 4 Sensitization to cockroach allergen analyzed in terms of the subject’s SES (A), race nested within SES (B), and residence nested within SES (C). SES was significantly associated with cockroach sensitization (p < 0.001). A significant difference in race was seen only in the middle SES (p < 0.001). Urban versus suburban residence did not show any difference in any of the three SES groups. Journal of Allergy and Clinical Immunology 1996 97, 1393-1401DOI: (10.1016/S0091-6749(96)70209-9) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 4 Sensitization to cockroach allergen analyzed in terms of the subject’s SES (A), race nested within SES (B), and residence nested within SES (C). SES was significantly associated with cockroach sensitization (p < 0.001). A significant difference in race was seen only in the middle SES (p < 0.001). Urban versus suburban residence did not show any difference in any of the three SES groups. Journal of Allergy and Clinical Immunology 1996 97, 1393-1401DOI: (10.1016/S0091-6749(96)70209-9) Copyright © 1996 Mosby, Inc. Terms and Conditions

FIG. 4 Sensitization to cockroach allergen analyzed in terms of the subject’s SES (A), race nested within SES (B), and residence nested within SES (C). SES was significantly associated with cockroach sensitization (p < 0.001). A significant difference in race was seen only in the middle SES (p < 0.001). Urban versus suburban residence did not show any difference in any of the three SES groups. Journal of Allergy and Clinical Immunology 1996 97, 1393-1401DOI: (10.1016/S0091-6749(96)70209-9) Copyright © 1996 Mosby, Inc. Terms and Conditions