Cardiothoracic Transplantation: Recent Developments

Slides:

Advertisements

Similar presentations

HEART TRANSPLANTATION Pediatric Recipients 2010 ISHLT J Heart Lung Transplant Oct; 29 (10):

Advertisements

THE PATIENT’S JOURNEY TO TRANSPLANT AND BEYOND

Organ Donation and Transplantation Strategic Performance Update Sally Johnson 26 March 2015.

Organ Donation & Transplantation in Ireland – Changing times Aileen Counihan Transplant Co-ordinator Beaumont Hospital Beaumont Hospital.

Donor Utilization: Making Use of a Precious Resource in Cardiac Transplant Jason W. Smith, MD Assistant Professor of Surgery The University of Washington.

Harefield DCD heart transplant programme

Allocation of elderly deceased donor kidneys Lisa Bradbury, Niaz Ahmad, Paul Gibbs, Richard Baker, Adam McLean, Chris Callaghan Renal Transplant Services.

Midlands Regional Data Jonathan Thompson CLOD for University Hospitals of Leicester NHS Trust & East Midlands.

BWGHF Liège Heart transplantation 2008.

Eurotransplant: An example of success for cross-border cooperation Bruno Meiser Eurotransplant International Foundation, Leiden, Netherlands Dept. of Cardiac.

Improving the utility of comorbidity records Retha Steenkamp UK Renal Registry.

UK Renal Registry 17th Annual Report Figure Percentage of patients waitlisted for a kidney transplant by renal centre, prior to or within two years.

Organ Donation and Transplantation in Paediatrics.

Liver Transplantation

13th OCT Teaching Nisha Talwar FY2. Chronic activation of RAAS and adrengic systems results in a vicious cycle that further exacerbates physiological.

 Kidney  Pancreas  Liver  Heart 1954 by Murray/Harrison 1966 by Lillehei 1967 by Starzl 1968 by Barnard.

OPTN Proposal to Revise the Lung Allocation Score (LAS) System and Salient Activities of the Thoracic Organ Transplantation Committee.

Scottish Renal Registry Report 2009 Section D - Kidney Transplantation Published by the Information Services Division (ISD Scotland), Common Services Agency.

Can we improve deceased donor kidney utilisation? Chris Callaghan National Clinical Lead for Abdominal Organ Utilisation, NHSBT Consultant Transplant Surgeon,

New kidney offering scheme … Lorna Marson Deputy Chair, Kidney Advisory Group Work in progress.

THE AUSTRALIA AND NEW ZEALAND CARDIOTHORACIC ORGAN TRANSPLANT REGISTRY

ODT - International Benchmarking

Evan P. Kransdorf, MD, PhD, Michelle M. Kittleson, MD, PhD, Jignesh K

Figure 1. Rate of antimicrobial resistance in S. pneumoniae

Fig 1 Trends in organ donors in the UK, 2000–10

Strategies to increase transplantation

Journal of Transplantation Technologies & Research

Integrating Cancer care into HIV care

Table 1 Cause of death for arrested organ donors

Fig. 3 Overall and disease-free survival of single-zone metastasis group according to the number of stations involved. No significant differences were.

UK Renal Registry 15th Annual Report

2015 Kidney Allocation Task Force HLA Working Group

Organ Utilisation Strategy

T. Rana, L. Szabo, A. Asderakis, E. Ablorsu

Updates on the New Adult Heart Allocation System

Liver only transplants in the UK Question 2: In terms of survival benefit.

Liver transplantation using Donation after Cardiac Death donors

HEART-LUNG TRANSPLANTATION

Kidney allocation in the UK

(1) Donor and Transplant Activity There has been an increase in the number of liver donors since 2007/08, with a concurrent mean 12% increase in.

HEART TRANSPLANTATION

HEART TRANSPLANTATION

Your ethnic background influences your genetic make up - that means you’re more likely to be a matching donor for someone who shares your ethnic heritage.

Risk factors in deceased-donor transplants Risk factor 1988

Towards a framework for organ donation in the UK

ODT Hub Programme Update National Organ Donation Committee Feb 2018 Jacki Newby Head of Referral and Offering 1.

Renal transplantation at Royal Wolverhampton Hospitals Trust

HEART-LUNG TRANSPLANTATION

UK Renal Registry 13th Annual Report

THE AUSTRALIA AND NEW ZEALAND CARDIOTHORACIC ORGAN TRANSPLANT REGISTRY

KQuIP Transplant first- Living kidney donor transplantation

HEART-LUNG TRANSPLANTATION

Thoracic Organ Transplantation Committee

Teaching first year medical students together

HEART-LUNG TRANSPLANTATION

Graphs from annual report 2018

General Imaging Information

Organ transplantation: historical perspective and current practice

Paediatric Donors and Transplant Patients

The Latest Intestinal Transplant Data

Midlands Organ Donation Services Team

Liver Transplant Data for Regional Meetings

Philosophy of Organ Allocation

HEART-LUNG TRANSPLANTATION

Heart: Year in Review OSOTC 2018 Transplant Symposium September 7, 2018 Brent C. Lampert, DO, FACC Medical Director, Heart Transplantation and Mechanical.

Illustrative Performance Improvement Targets

UK Renal Registry 16th Annual Report

The Heart Truth Delaware Background

Deceased solid organ donors Recent trends from ANZOD

HEART-LUNG TRANSPLANTATION

Presentation transcript:

Cardiothoracic Transplantation: Recent Developments Sally Rushton Statistics and Clinical Studies NHS Blood and Transplant BTS Congress, March 2019

Outline Overview of cardiothoracic transplant programmes Trends in adult heart transplant activity Trends in adult lung transplant activity Donor organ utilisation Patient focussed reporting

Outline Overview of cardiothoracic transplant programmes Trends in adult heart transplant activity Trends in adult lung transplant activity Donor organ utilisation Patient focussed reporting

Cardiothoracic Transplant Programmes Heart Lung

Outline Overview of cardiothoracic transplant programmes Trends in adult heart transplant activity Trends in adult lung transplant activity Donor organ utilisation Patient focussed reporting

Adult heart transplants performed in the UK 72% increase

Adult heart transplants - by donor type Patient survival post-transplant (2015-18) DBD DCD 83% survival at 1 year p=0.95

Adult heart transplants - by urgency Super-urgent scheme Oct 2016 Median waiting time to transplant (95% CI) DAYS Super-urgent 9 (6-12) Urgent 52 (38-66) Non-urgent 502 (379-625)

Adult heart transplants - by urgency Super-urgent scheme Oct 2016 Patient survival post-transplant (2015-18) Non-urgent Urgent Super-urgent p=0.6 1 year % (95% CI) 85 (76-91) 83 (79-87) 78 (63-88)

Outline Overview of cardiothoracic transplant programmes Trends in adult heart transplant activity Trends in adult lung transplant activity Donor organ utilisation Patient focussed reporting

Adult lung transplants performed in the UK 51% increase

Adult lung transplants - by transplant type

Adult lung transplants - by donor type Patient survival post-transplant (2013-17) DBD DCD p=0.2 2 years % (95% CI) 73 (69-76) 67 (58-75)

Adult lung only transplants - by urgency Urgent and super-urgent schemes May 2017 Median waiting time to transplant (95% CI) DAYS Super-urgent 8 (0-19) Urgent 23 (14-32) Non-urgent 531 (412-650)

Adult lung only transplants - by urgency Patient survival post-transplant (2017/18) Urgent and super-urgent schemes May 2017 Non-urgent Urgent/Super-urgent p=0.04 12 months % (95% CI) 86 (79-91) 74 (58-84)

Outline Overview of cardiothoracic transplant programmes Trends in adult heart transplant activity Trends in adult lung transplant activity Donor organ utilisation Patient focussed reporting

Percentage of DBD organs offered that were transplanted Heart Lung N= 451 451 474 435 460 474 480 457 511 546 N= 484 491 502 477 521 549 545 526 530 581

Percentage of “ideal” DBD organs offered that were transplanted Heart Lung N= 88 90 103 80 88 80 84 75 65 76 N= 80 80 93 80 70 88 84 78 72 88 DBDs <56, no past cardiac disease, normal ECG, negative serology, non-smoker, no history of hypertension or diabetes (CTAG) DBDs <56, non-smoker, normal x-ray, max pO2>40 (Agence de Biomedecine)

Outline Overview of cardiothoracic transplant programmes Trends in adult heart transplant activity Trends in adult lung transplant activity Donor organ utilisation Patient focussed reporting

Infographics Available on www.odt.nhs.uk soon

Infographics Available on www.odt.nhs.uk soon

Acknowledgements Members of the Cardiothoracic Advisory Group Chloe Brown and Rachel Hogg, Statistics and Clinical Studies Sally.Rushton@nhsbt.nhs.uk