Volume 62, Issue 6, Pages (December 2002)

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Presentation transcript:

Volume 62, Issue 6, Pages 2202-2207 (December 2002) A randomized controlled trial of N-acetylcysteine to prevent contrast nephropathy in cardiac angiography John D. Durham, Christopher Caputo, John Dokko, Thomas Zaharakis, Mohsen Pahlavan, Jan Keltz, Paula Dutka, Kevin Marzo, John K. Maesaka, Steven Fishbane Kidney International Volume 62, Issue 6, Pages 2202-2207 (December 2002) DOI: 10.1046/j.1523-1755.2002.00673.x Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 1 Acute renal failure developed in a similar number of patients in the N-acetylcysteine (NAC) and placebo groups. In patients with diabetes mellitus, there was statistically significant difference, but a notable trend to greater risk for acute renal failure (ARF) in the NAC group. Kidney International 2002 62, 2202-2207DOI: (10.1046/j.1523-1755.2002.00673.x) Copyright © 2002 International Society of Nephrology Terms and Conditions

Figure 2 Change from pre-angiography to 48 hours post-angiography levels of serum creatinine in individual patients in the placebo and NAC groups. Kidney International 2002 62, 2202-2207DOI: (10.1046/j.1523-1755.2002.00673.x) Copyright © 2002 International Society of Nephrology Terms and Conditions