Visual validation of the computational outputs. Visual validation of the computational outputs. (A) Charge state correction. Users can adjust/correct the charge state to better fit the data and acquire accurate mass values. (B) Mass shift correction. Users can shift the theoretical isotopomer envelope incrementally by 1 Dalton to fit the real spectrum for obtaining accurate mass values. Wenxuan Cai et al. Mol Cell Proteomics 2016;15:703-714 © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.