Schematic illustration of the assembly and interactions of sperm-bound eppin protein complex (EPC) components. Schematic illustration of the assembly and.

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Schematic illustration of the assembly and interactions of sperm-bound eppin protein complex (EPC) components. Schematic illustration of the assembly and interactions of sperm-bound eppin protein complex (EPC) components. EPN, eppin; CLU, clusterin; LTF, lactotransferrin; SEMG1, semenogelin-1. Because of limited data availability, stoichiometric aspects of EPC subunit composition and assembly have not been considered. Disulfide bonds that appear to be critical for EPC structure and function are indicated (CysX, cysteine residue of the eppin75–133 C-terminal fragment (39); CysA, CysB, cysteine residues of clusterin α and β subunits, respectively). Uwe Paasch et al. Mol Cell Proteomics 2011;10:M110.007187 © 2011 by The American Society for Biochemistry and Molecular Biology, Inc.