Hematological alterations after endotoxin injection.

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Hematological alterations after endotoxin injection. Hematological alterations after endotoxin injection. (A) Humans have an overall increase in circulating WBCs, while the murine response is virtually unchanged. Neutrophilia (B) and lymphopenia (C) develop in mice and humans. In panels B and C, the human and mouse data are plotted on different scales, since the number of circulating cells differs in mice and humans. Each value is the mean ± SEM (error bar) for 10 humans or 23 mice. Shannon Copeland et al. Clin. Diagn. Lab. Immunol. 2005; doi:10.1128/CDLI.12.1.60-67.2005