Unfolded protein response Stewart Siyan Cao, Randal J. Kaufman  Current Biology  Volume 22, Issue 16, Pages R622-R626 (August 2012) DOI: 10.1016/j.cub.2012.07.004 Copyright © 2012 Elsevier Ltd Terms and Conditions

Figure 1 The unfolded protein response in mammals. See main text for details. Current Biology 2012 22, R622-R626DOI: (10.1016/j.cub.2012.07.004) Copyright © 2012 Elsevier Ltd Terms and Conditions

Figure 2 Endoplasmic reticulum stress in human disease. A number of human diseases are associated with ER protein-folding defects and the UPR. Studies of ER stress and the UPR should enhance our understanding of the pathogenesis of these diseases and open up new avenues to therapeutic approaches. Current Biology 2012 22, R622-R626DOI: (10.1016/j.cub.2012.07.004) Copyright © 2012 Elsevier Ltd Terms and Conditions