Malassezia globosa and restricta: Breakthrough Understanding of the Etiology and Treatment of Dandruff and Seborrheic Dermatitis through Whole-Genome.

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Presentation transcript:

Malassezia globosa and restricta: Breakthrough Understanding of the Etiology and Treatment of Dandruff and Seborrheic Dermatitis through Whole-Genome Analysis Thomas L. Dawson Journal of Investigative Dermatology Symposium Proceedings Volume 12, Issue 2, Pages 15-19 (December 2007) DOI: 10.1038/sj.jidsymp.5650049 Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Relative composition of human sebum. (reprinted from Ro and Dawson, 2005) Journal of Investigative Dermatology Symposium Proceedings 2007 12, 15-19DOI: (10.1038/sj.jidsymp.5650049) Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 2 A model of the role of Malassezia lipase-mediated hydrolysis of scalp lipids in the etiology of dandruff and seborrheic dermatitis. Some fatty acids are consumed by the fungal cells, whereas other fatty acids cause scalp irritation. (reprinted from DeAngelis et al., 2007) Journal of Investigative Dermatology Symposium Proceedings 2007 12, 15-19DOI: (10.1038/sj.jidsymp.5650049) Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions