Recommendations for the management of patients with homozygous familial hypercholesterolaemia: Overview of a new European Atherosclerosis Society consensus.

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Recommendations for the management of patients with homozygous familial hypercholesterolaemia: Overview of a new European Atherosclerosis Society consensus statement Eric Bruckert Atherosclerosis Supplements Volume 15, Issue 2, Pages 26-32 (September 2014) DOI: 10.1016/j.atherosclerosissup.2014.07.004 Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Number of publications on homozygous familial hypercholesterolaemia identified using PubMed in March 2013, shown by year from 2007 to 2012. Atherosclerosis Supplements 2014 15, 26-32DOI: (10.1016/j.atherosclerosissup.2014.07.004) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 The heterogeneity of homozygous familial hypercholesterolaemia. Atherosclerosis Supplements 2014 15, 26-32DOI: (10.1016/j.atherosclerosissup.2014.07.004) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 3 Reduction in low-density lipoprotein cholesterol in patients with homozygous familial hypercholesterolaemia receiving statin therapy alone or in combination with ezetimibe (EZE) [11]. †All patients were receiving statin 40 mg at baseline and prior to switch; *p = 0.02 versus statin only 80 mg; **p < 0.01 versus statin only 80 mg. Atherosclerosis Supplements 2014 15, 26-32DOI: (10.1016/j.atherosclerosissup.2014.07.004) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 4 Estimation of low-density lipoprotein cholesterol (LDL-C) levels achieved upon treatment with current therapies in patients with homozygous familial hypercholesterolaemia, according to the severity of the disease. Atherosclerosis Supplements 2014 15, 26-32DOI: (10.1016/j.atherosclerosissup.2014.07.004) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions