Effect of Haemophilus influenzae type b vaccination without a booster dose on invasive H influenzae type b disease, nasopharyngeal carriage, and population.

Slides:

Advertisements

Similar presentations

Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study Dr Andrew C Hayward, MD, Ellen B.

Advertisements

Prevalence of pulmonary tuberculosis in western China in 2010–11: a population-based, cross-sectional survey Peierdun Mijiti, PhD, Li Yuehua, MD, Xue.

Volume 383, Issue 9920, Pages (March 2014)

Volume 14, Issue 1, Pages (January 2015)

Socioeconomic inequality in neonatal mortality in countries of low and middle income: a multicountry analysis Britt McKinnon, MSc, Sam Harper, PhD, Prof.

Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis Wan Ling.

Risk of cancer associated with residential exposure to asbestos insulation: a whole- population cohort study Dr Rosemary J Korda, PhD, Mark S Clements,

Estimating trends in life expectancy in HIV-positive individuals

Active surveillance for rheumatic heart disease in endemic regions: a systematic review and meta-analysis of prevalence among children and adolescents

Effects of the introduction of new vaccines in Guinea-Bissau on vaccine coverage, vaccine timeliness, and child survival: an observational study Dr Ane.

Paul K Drain, Nigel J Garrett The Lancet Global Health

Burden of disease in adults admitted to hospital in a rural region of coastal Kenya: an analysis of data from linked clinical and demographic surveillance.

Pneumococcal conjugate vaccine 13 delivered as one primary and one booster dose (1 + 1) compared with two primary doses and a booster (2 + 1) in UK infants:

Sensitivity and specificity of a rapid point-of-care test for active yaws: a comparative study Telek Ayove, BSc, Wendy Houniei, HEO, Regina Wangnapi,

Maternal and perinatal mortality in resource-limited settings

SubbaRao M Gavaravarapu, Katherine C Smith, Rajiv N Rimal

Veterinary medicine's increasing role in global health

Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study Dr Andrew C Hayward, MD, Ellen B.

Burden of childhood tuberculosis in 22 high-burden countries: a mathematical modelling study Dr Peter J Dodd, PhD, Elizabeth Gardiner, MSc, Renia Coghlan,

Mapping HIV epidemics in sub-Saharan Africa with use of GPS data

Prevalence of drug and alcohol use in urban Afghanistan: epidemiological data from the Afghanistan National Urban Drug Use Study (ANUDUS) Dr Linda B.

Socioeconomic disparities in first stroke incidence, quality of care, and survival: a nationwide registry-based cohort study of 44 million adults in England

Mortality and its risk factors in Malawian children admitted to hospital with clinical pneumonia, 2001–12: a retrospective observational study Dr Marzia.

Volume 383, Issue 9920, Pages (March 2014)

Paediatric mortality related to pandemic influenza A H1N1 infection in England: an observational population-based study Nabihah Sachedina, MBBS, Prof.

Tackling stigma: fundamental to an AIDS-free future

Effect of a community-led sanitation intervention on child diarrhoea and child growth in rural Mali: a cluster-randomised controlled trial Dr Amy J Pickering,

Economic opportunity, health behaviours, and health outcomes in the USA: a population-based cross-sectional study Dr Atheendar S Venkataramani, MD, Rachel.

Effect of antenatal multiple micronutrient supplementation on anthropometry and blood pressure in mid-childhood in Nepal: follow-up of a double-blind.

Measuring health and economic wellbeing in the Sustainable Development Goals era: development of a poverty-free life expectancy metric and estimates for.

National, regional, and global sex ratios of infant, child, and under-5 mortality and identification of countries with outlying ratios: a systematic assessment

Orientia, rickettsia, and leptospira pathogens as causes of CNS infections in Laos: a prospective study Sabine Dittrich, PhD, Sayaphet Rattanavong, MD,

Health consequences of exposure to e-waste: a systematic review

Socioeconomic inequality in neonatal mortality in countries of low and middle income: a multicountry analysis Britt McKinnon, MSc, Sam Harper, PhD, Prof.

Trends in infant mortality in Venezuela between 1985 and 2016: a systematic analysis of demographic data Jenny García, MSc, Prof Gerardo Correa, MSc,

Population effect of 10-valent pneumococcal conjugate vaccine on nasopharyngeal carriage of Streptococcus pneumoniae and non-typeable Haemophilus influenzae.

Addressing the neglect: Chagas disease in London, UK

Effects of health-system strengthening on under-5, infant, and neonatal mortality: 11- year provincial-level time-series analyses in Mozambique Quinhas.

Prevalence of and factors associated with non-partner rape perpetration: findings from the UN Multi-country Cross-sectional Study on Men and Violence.

Prevalence of and risk factors for active tuberculosis in migrants screened before entry to the UK: a population-based cross-sectional study Dr Robert.

Effect of ten-valent pneumococcal conjugate vaccine on invasive pneumococcal disease and nasopharyngeal carriage in Kenya: a longitudinal surveillance.

Tobacco use in pregnant women: analysis of data from Demographic and Health Surveys from 54 low-income and middle-income countries Dr Rishi Caleyachetty,

Burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national.

Classification of global measles cases in 2013–17 as due to policy or vaccination failure: a retrospective review of global surveillance data Minal K.

Daily co-trimoxazole prophylaxis to prevent mortality in children with complicated severe acute malnutrition: a multicentre, double-blind, randomised.

Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis Wan Ling.

Effect of daily iron supplementation on health in children aged 4–23 months: a systematic review and meta-analysis of randomised controlled trials Dr.

Burden of childhood tuberculosis in 22 high-burden countries: a mathematical modelling study Dr Peter J Dodd, PhD, Elizabeth Gardiner, MSc, Renia Coghlan,

Effect of ten-valent pneumococcal conjugate vaccine introduction on pneumococcal carriage in Fiji: results from four annual cross-sectional carriage surveys

Life expectancy among HIV-positive patients in Rwanda: a retrospective observational cohort study Sabin Nsanzimana, MD, Eric Remera, MSc, Steve Kanters,

Key issues in the persistence of poliomyelitis in Nigeria: a case-control study Dr Tara D Mangal, PhD, R Bruce Aylward, MD, Michael Mwanza, BComm, Alex.

Prevalence of pulmonary tuberculosis in western China in 2010–11: a population-based, cross-sectional survey Peierdun Mijiti, PhD, Li Yuehua, MD, Xue.

Thank you to our diverse (but not diverse enough) reviewers

Global economic consequences of selected surgical diseases: a modelling study Dr Blake C Alkire, MD, Mark G Shrime, MD, Anna J Dare, PhD, Prof Jeffrey.

Incidence and severity of childhood pneumonia in the first year of life in a South African birth cohort: the Drakenstein Child Health Study Dr David.

Metformin for non-diabetic patients with coronary heart disease (the CAMERA study): a randomised controlled trial Dr David Preiss, PhD, Suzanne M Lloyd,

Effect of 10-valent pneumococcal conjugate vaccine on the incidence of radiologically- confirmed pneumonia and clinically-defined pneumonia in Kenyan children:

Effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction: an observational.

Kathleen M Neuzil, Karen L Kotloff The Lancet Global Health

Double burden of tragedy: stillbirth and obstetric fistula

Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant.

Effect of Haemophilus influenzae type b vaccination without a booster dose on invasive H influenzae type b disease, nasopharyngeal carriage, and population.

Age-targeted tuberculosis vaccination in China and implications for vaccine development: a modelling study Rebecca C Harris, PhD, Tom Sumner, PhD, Gwenan.

Volume 378, Issue 9799, Pages (October 2011)

Sustaining pneumococcal vaccination after transitioning from Gavi support: a modelling and cost-effectiveness study in Kenya John Ojal, PhD, Ulla Griffiths,

Effects of recurrent violence on post-traumatic stress disorder and severe distress in conflict-affected Timor-Leste: a 6-year longitudinal study Dr.

Is the pharmaceutical industry improving with regard to access to essential medicines? Hans V Hogerzeil, Jayasree K Iyer, Lisanne Urlings, Tara Prasad,

Burden of sickle cell trait and disease in the Uganda Sickle Surveillance Study (US3): a cross-sectional study Grace Ndeezi, MBChB PhD, Charles Kiyaga,

Effect of strikes by health workers on mortality between 2010 and 2016 in Kilifi, Kenya: a population-based cohort analysis Gerald Ong'ayo, MBChB, Michael.

Wolfgang Högler, Craig F Munns The Lancet Global Health

Presentation transcript:

Effect of Haemophilus influenzae type b vaccination without a booster dose on invasive H influenzae type b disease, nasopharyngeal carriage, and population immunity in Kilifi, Kenya: a 15-year regional surveillance study Dr Laura L Hammitt, MD, Rosie J Crane, MBBS, Angela Karani, BSc, Alex Mutuku, MSc, Susan C Morpeth, FRACP, Polly Burbidge, BSc, Prof David Goldblatt, MB ChB, Tatu Kamau, MPH, Shahnaaz Sharif, MD, Neema Mturi, MRCPCH, Prof J Anthony G Scott, FRCP The Lancet Global Health Volume 4, Issue 3, Pages e185-e194 (March 2016) DOI: 10.1016/S2214-109X(15)00316-2 Copyright © 2016 Hammitt et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 1 Incidence of invasive Haemophilus influenzae type b disease in children younger than 5 years in the Kilifi Health and Demographic Surveillance System, 2000–14 Hib vaccine was introduced in November, 2001. Error bars show 95% CI. The Lancet Global Health 2016 4, e185-e194DOI: (10.1016/S2214-109X(15)00316-2) Copyright © 2016 Hammitt et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 2 Children with anti-PRP concentrations of >1 μg/mL, by age group and survey year Data for 1998 and 2000 combined (A), 2004–05 (B), 2007 (C), and 2009 (D). The proportion of children aged 4–7 months in (A) is 0%. Error bars show 95% CI. PRP=polyribosylribitol phosphate. The Lancet Global Health 2016 4, e185-e194DOI: (10.1016/S2214-109X(15)00316-2) Copyright © 2016 Hammitt et al. Open Access article distributed under the terms of CC BY Terms and Conditions

Figure 3 Reverse cumulative proportions of children with anti-PRP concentrations that exceed thresholds, by age group and survey year Data for children aged 4–11 months (A) 1–2 years (B), 3–4 years (C), and 5–12 years (D). Vertical lines indicate thresholds for short-term (0·15 μg/mL) and long-term (1 μg/mL) protection against invasive H influenzae type b disease. The Lancet Global Health 2016 4, e185-e194DOI: (10.1016/S2214-109X(15)00316-2) Copyright © 2016 Hammitt et al. Open Access article distributed under the terms of CC BY Terms and Conditions