CTEPH in Clinical Practice

Slides:



Advertisements
Similar presentations
AM Report Lauren Galpin, MD MA  “Thromboembolic obstruction of the major pulmonary arteries due to unresolved pulmonary embolism [with pulmonary.
Advertisements

What You Need to Know About CTEPH Today: A Status Update Moderator David Langleben, MD, FRCPC Professor of Medicine McGill University Director Center for.
Latin American Symposium Future Perspectives in Pulmonary Hypertension.
A story of acute myocardial infarction.. By: Dr. Walid Kamel Ass. Lecturer Critical Care Cairo University.
CRT 2012 Venous Disease.
Pulmonary hypertension
Multimodal Management of Opioid-Induced Constipation
Upfront Combination Therapy vs Step-Up Approach for PAH:
A strange post-CABG presentation
Pulmonal hypertensjon
D-dimer and helical CT-PA based diagnostic algorithm for PE
A Framework for Diagnosing and Treating CTEPH
Update on the Diagnosis and Management of CTEPH in Latin America
Volume 150, Issue 3, Pages (September 2016)
Identifying and Managing Dyspnea Associated With CTEPH
Challenges in the Diagnosis of MS: Physician and Nurse Perspectives
Glaucoma Progression.
Victor F. Tapson, MD, David M. Platt, MD, Fang Xia, PhD, Simon A
UNDERSTANDING RISK STRATIFICATION IN PAH:
Protecting Patients With Varicose Veins
Epidemiology Venous Pathophysiology Etiology.
Case Challenges in Chronic Migraine
Pulmonary Embolism Scope of the Problem Massive vs Submassive Pulmonary Embolism.
New Treatments for CTEPH
Follow-Up of the Patient After PE
The Complete Health Assessment: Putting It All Together
PAH in Adults CHEST Guideline and Expert Panel Report: Grading of Evidence
Updates in Pulmonary Arterial Hypertension
WHO Clinical Classification of PH Complex Cases in PH.
Program Goals. Treatment-Naive Patients With PAH What Do We Know and What Choices Do We Have?
Evolving Science of PAH Treatment
2013 World Symposium on PH CTEPH Diagnosisa 2013 World Symposium on PH (cont) CTEPH Treatmenta.
Oral Anticoagulation in AF
Pseudobulbar Affect or Psychiatric Condition?
Using Heart Rate as a Biomarker in Clinical Practice.
POSTERIOR VIEW SKELETON ANTERIOR.
Current and Emerging Data in CTEPH
Case Study 56-year-old Presents With 1 Year of Worsening Dyspnea
The Complete Health Assessment: Putting It All Together
Identifying Strategies for Improving Outcomes in Patients With CTEPH
PAH Treatment.
PEARLS OF WISDOM WITH COMBINATION THERAPY IN PAH
Familial Chronic Thromboembolic Pulmonary Hypertension
NOAC Studies in VTE AF Studies Superior Outcomes.
Pulmonary Hypertension Updates From 2018
The management options for chronic thromboembolic pulmonary hypertension (CTEPH) target different pathogenic manifestations in different parts of the pulmonary.
Program Goals Background: Anticoagulation in Patients With VTE.
Operability assessment in CTEPH: Lessons from the CHEST-1 study
Treatment algorithm for managing chronic thromboembolic pulmonary hypertension (CTEPH), from the European Society of Cardiology/European Respiratory Society.
Patient Stories in PAH: Sequential Therapy in a FC II Patient
Disease Burden of VTE Phases of VTE Treatment.
Prostacyclin Pathway Agents in Action
Diagnostic imaging of distal chronic thromboembolic pulmonary hypertension lesions. a) Ventilation/perfusion scintigraphy. b) Conventional pulmonary angiography.
Incorporating New PAH Treatments Into Clinical Practice
Clinical Comparisons in CTEPH
A Closer Look.
Mean change from baseline in 6MWD in (A) Chinese patients with PAH in PATENT-1 and (B) Chinese patients with CTEPH in CHEST-1. Mean change from baseline.
Pulmonary angiography in the right lung (a, c, e and g) and the left lung (b, d, f and h) of a patient with chronic thromboembolic pulmonary hypertension.
Definition of pulmonary hypertension (PH) associated with left heart disease. mPAP: mean pulmonary arterial pressure; PAWP: pulmonary artery wedge pressure;
A) Conventional pulmonary angiogram, with b) and c) corresponding optical coherence tomography images from a patient with chronic thromboembolic pulmonary.
Example scans for a typical patient with operable chronic thromboembolic pulmonary hypertension. a) Perfusion (Q′) and b) ventilation (V′) lung scans.
A) Annual diagnosed incidence of pulmonary embolism (PE), and b) annual full incidence of chronic thromboembolic pulmonary hypertension (CTEPH) per 100 000.
Cardiac index (CI) changes from baseline following single oral doses of riociguat (○) 1 mg and 2.5 mg compared with inhaled nitric oxide (•) in patients.
Diagnostic algorithm for chronic thromboembolic pulmonary hypertension
The Real Burden of Rosacea
Patient with inoperable chronic thromboembolic pulmonary hypertension showing a typical aspect of subpleural hypoperfusion at the capillary phase of pulmonary.
Advances in Portopulmonary Hypertension
Treatment algorithm for chronic thromboembolic pulmonary hypertension.
Treating Pulmonary Embolism Today
Cardiac index (CI) changes from baseline following single oral doses of riociguat (Rio) compared with inhaled nitric oxide (NO) in patients with chronic.
Presentation transcript:

CTEPH in Clinical Practice

Chronic Thromboembolic Pulmonary Hypertension (CTEPH) -- Background

Patient Case 1 -- Operable CTEPH 65-Year-Old Male Patient With a History of DVT and PE

Pathophysiology of CTEPH

Diagnostic Algorithm For CTEPH

Patient Case 1 Pulmonary Angiogram in Anterior-Posterior View

Patient Case 1 Pulmonary Angiogram Lateral View

Pulmonary Thromboendarterectomy (PEA)

Patient Case 1 PEA

CTEPH in Real Life Data From Bad Nauheim 3/2014 - 2/2016

Patient Case 2 -- Inoperable CTEPH Male Patient (b Patient Case 2 -- Inoperable CTEPH Male Patient (b. 1977) With Neurological Malignant Disorder

Patient Case 2 -- Inoperable CTEPH Follow-Up Angiography in 2015

Patient Case 2 What Makes the Patient Inoperable?

Patient Case 2 Treatment Plan

CHEST-1 Riociguat in Patients With CTEPH

MERIT-1 Macitentan in Patients With CTEPH

BENEFiT: Bosentan in Patient With CTEPH

Balloon Pulmonary Angioplasty (BPA)

Hybrid Interventions in CTEPH

Sequential Treatment With Riociguat and BPA for Patients With Inoperable CTEPH

Take-Home Messages

Abbreviations

Abbreviations (cont)