Richard J. Novick, MDa, Ruud A. W

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Presentation transcript:

Exogenous surfactant therapy in thirty-eight hour lung graft preservation for transplantation  Richard J. Novick, MDa, Ruud A.W. Veldhuizen, PhDb, Fred Possmayer, PhDc, John Lee, MDa, David Sandler, MDa, James F. Lewis, MDb  The Journal of Thoracic and Cardiovascular Surgery  Volume 108, Issue 2, Pages 259-268 (August 1994) DOI: 10.5555/uri:pii:S0022522394700087 Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 1 Po 2/Fio 2 ratio of control dogs (mean ± standard error of the mean) and each surfactant-treated dog. Three surfactant-treated animals had near normal oxygenation by the end of reperfusion. TX, Transplantation. The Journal of Thoracic and Cardiovascular Surgery 1994 108, 259-268DOI: (10.5555/uri:pii:S0022522394700087) Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 2 Changes in Pco 2 (A) and peak inspired pressure (PIP) (B) during reperfusion (mean ± standard error of the mean). TX, Transplantation. The Journal of Thoracic and Cardiovascular Surgery 1994 108, 259-268DOI: (10.5555/uri:pii:S0022522394700087) Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 3 Changes in left pulmonary blood flow (as a percentage of pretransplantation baseline) during reperfusion (mean ± standard error of the mean). TX, Transplantation. The Journal of Thoracic and Cardiovascular Surgery 1994 108, 259-268DOI: (10.5555/uri:pii:S0022522394700087) Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 4 Protein yield in lung lavages from donor right lungs (DONOR), transplanted left lungs (TRANSPLANT), and native right lungs (NATIVE) of recipient animals. The Journal of Thoracic and Cardiovascular Surgery 1994 108, 259-268DOI: (10.5555/uri:pii:S0022522394700087) Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 5 Surfactant small/large aggregate ratio in donor right lungs (DONOR), transplanted left lungs (TRANSPLANT), and native right lungs (NATIVE) of recipient animals. The Journal of Thoracic and Cardiovascular Surgery 1994 108, 259-268DOI: (10.5555/uri:pii:S0022522394700087) Copyright © 1994 Mosby, Inc. Terms and Conditions