Forced convective head cooling device reduces human cross-sectional brain temperature measured by magnetic resonance: a non-randomized healthy volunteer.

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Forced convective head cooling device reduces human cross-sectional brain temperature measured by magnetic resonance: a non-randomized healthy volunteer pilot study B.A. Harris, P.J.D. Andrews, I Marshall, T.M. Robinson, G.D. Murray British Journal of Anaesthesia Volume 100, Issue 3, Pages 365-372 (March 2008) DOI: 10.1093/bja/aem405 Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

Fig 1 Axial T2-weighted image at the level of the basal ganglia, overlaid with the spectroscopic grid showing the region boundaries drawn in red, blue and green. Each numbered square on the grid corresponds to one voxel. Core voxels are within the green line, intermediate voxels between the green and blue lines, and outer voxels between the blue and red lines. British Journal of Anaesthesia 2008 100, 365-372DOI: (10.1093/bja/aem405) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

Fig 2 An example of a voxel temperature map at baseline, overlaid on the corresponding axial T2-weighted image at the level of the basal ganglia. Each numbered square represents one voxel and the colour of the voxel represents the temperature in that voxel. The temperature scale is given in degrees Celsius. British Journal of Anaesthesia 2008 100, 365-372DOI: (10.1093/bja/aem405) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

Fig 3 Baseline corrected mean MRS temperature (°C) (a) with head cooling and head and neck cooling over all voxels for all subjects, (b) with head cooling over outer, intermediate, and core voxels for all subjects, (c) with head and neck cooling over outer, intermediate, and core voxels for all subjects. (d) Mean forearm minus fingertip temperature difference (°C) over final minute of baseline and each cooling intervention. British Journal of Anaesthesia 2008 100, 365-372DOI: (10.1093/bja/aem405) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions