Ala16Val SOD2 polymorphism is associated with higher pregnancy rates in in vitro fertilization cycles  José Ignacio Ruiz-Sanz, Ph.D., Igor Aurrekoetxea, Ph.D., Roberto Matorras, M.D., Ph.D., M. Begoña Ruiz-Larrea, Ph.D.  Fertility and Sterility  Volume 95, Issue 5, Pages 1601-1605 (April 2011) DOI: 10.1016/j.fertnstert.2010.11.022 Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

Figure 1 (A) Schematic illustration of the interactions between the template and polymerase chain reaction (PCR) primers for amplification refractory mutation system analysis of Ala16Val SOD2 polymorphism (GenBank accession no. AY267901). Exons are shown as black boxes and the corresponding introns appear as lines. Fragments are not drawn to scale. (B) Primers used in the polymorphism analysis. The 3′-end of the allele-specific primers is underlined. Underlined lowercase bases indicate the introduced mismatches. Fertility and Sterility 2011 95, 1601-1605DOI: (10.1016/j.fertnstert.2010.11.022) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Genotype and allele distribution of the Ala16Val SOD2 polymorphism, according to the achievement of pregnancy. Pregnancy, N = 44; No pregnancy, N = 104. Fertility and Sterility 2011 95, 1601-1605DOI: (10.1016/j.fertnstert.2010.11.022) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions