Sulfasalazine-Induced Crystalluria Causing Severe Acute Kidney Injury Michael Durando, MD, PhD, Hannah Tiu, MD, James Soo Kim, MD  American Journal of Kidney Diseases  Volume 70, Issue 6, Pages 869-873 (December 2017) DOI: 10.1053/j.ajkd.2017.05.013 Copyright © 2017 The Authors Terms and Conditions

Figure 1 Graph of patient’s serum creatinine and serum urea nitrogen (SUN) starting at his last recorded baseline (BL) value before admission, following his 7-day course in the hospital, and ending at his readmission 6 months later. American Journal of Kidney Diseases 2017 70, 869-873DOI: (10.1053/j.ajkd.2017.05.013) Copyright © 2017 The Authors Terms and Conditions

Figure 2 (A) Representative image from renal ultrasound shows calculi. Arrows indicate echogenic shadowing. See Item S1 for official radiology reports. (B) Macroscopic images of representative stones (later determined to be composed of sulfasalazine metabolites) voided by the patient. (C) Representative light microscopic image of a sulfasalazine metabolite calculus fragment after washing with deionized water and grinding on a glass slide (original magnification, ×60). American Journal of Kidney Diseases 2017 70, 869-873DOI: (10.1053/j.ajkd.2017.05.013) Copyright © 2017 The Authors Terms and Conditions